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2. Melatonin as a medication and supplement - Wikipedia

   en.wikipedia.org/wiki/Melatonin_as_a_medication...

   Increased use of melatonin in the 21st century has significantly increased reports of melatonin overdose, calls to poison control centers, and related emergency department visits for children. The number of children who unintentionally ingested melatonin supplements in the US has increased 530% from 2012 to 2021.

3. 1 in 5 children under the age of 14 take melatonin ... - AOL

   www.aol.com/1-5-children-under-age-011829011.html

   News of more families turning to melatonin to help restless kids comes after sleep specialists urged parents to consult doctors before melatonin use. 1 in 5 children under the age of 14 take ...

4. Clark's rule - Wikipedia

   en.wikipedia.org/wiki/Clark's_rule

   The procedure is to take the child's weight in pounds, divide by 150 lb, and multiply the fractional result by the adult dose to find the equivalent child dosage.For example, if an adult dose of medication calls for 30 mg and the child weighs 30 lb, divide the weight by 150 (30/150) to obtain 1/5 and multiply 1/5 times 30 mg to get 6 mg.

5. Melatonin - Wikipedia

   en.wikipedia.org/wiki/Melatonin

   Melatonin, an indoleamine, is a natural compound produced by various organisms, including bacteria and eukaryotes. [1] Its discovery in 1958 by Aaron B. Lerner and colleagues stemmed from the isolation of a substance from the pineal gland of cows that could induce skin lightening in common frogs .

6. You Shouldn’t Give Babies Melatonin, But Here’s ... - AOL

   www.aol.com/news/shouldn-t-babies-melatonin...

   Children can be notoriously bad sleepers, so who could blame a parent or caregiver for considering melatonin? Here’s what experts want you to know before giving it to kids, including safety ...

7. Experts Don't Actually Know If Melatonin Is Safe for ... - AOL

   www.aol.com/lifestyle/experts-dont-actually-know...

   Melatonin overdoses in kids are on the rise. A top sleep expert on inaccurate labels and what parents should do before using these supplements with their kids.

8. Equianalgesic - Wikipedia

   en.wikipedia.org/wiki/Equianalgesic

   Acute use (1–3 days) yields a potency about 1.5× stronger than that of morphine and chronic use (7 days+) yields a potency about 2.5 to 5× that of morphine. Similarly, the effect of tramadol increases after consecutive dosing due to the accumulation of its active metabolite and an increase of the oral bioavailability in chronic use.

9. Thousands of children are landing in the ER after ingesting ...

   www.aol.com/thousands-children-landing-er...

   Melatonin products have become increasingly popular among US adults and a new report from the US Centers for Disease Control and Prevention says about 11,000 children have landed in the emergency ...