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  2. Benzodiazepine withdrawal syndrome - Wikipedia

    en.wikipedia.org/wiki/Benzodiazepine_withdrawal...

    Withdrawal symptoms occur during dose reduction and may include insomnia, anxiety, distress, weight loss, dizziness, night sweats, shaking, muscle twitches, aphasia, panic attacks, depression, numbness,dissociation, paranoia, indigestion, diarrhea, and photophobia. As withdrawal progresses, patients often find their physical and mental health ...

  3. Opioid withdrawal - Wikipedia

    en.wikipedia.org/wiki/Opioid_withdrawal

    Opioid withdrawal is a set of symptoms (a syndrome) arising from the sudden cessation or reduction of opioids where previous usage has been heavy and prolonged. [1] [2] Signs and symptoms of withdrawal can include drug craving, anxiety, restless legs syndrome, nausea, vomiting, diarrhea, sweating, and an elevated heart rate. Opioid use triggers ...

  4. Effects of long-term benzodiazepine use - Wikipedia

    en.wikipedia.org/wiki/Effects_of_long-term...

    Although anxiety can temporarily increase as a withdrawal symptom, there is evidence that a reduction or withdrawal from benzodiazepines can lead to a reduction of anxiety symptoms in the long run. [ 4 ] [ 5 ] Due to these increasing physical and mental symptoms from long-term use of benzodiazepines, slow withdrawal is recommended for long-term ...

  5. Opioid use disorder - Wikipedia

    en.wikipedia.org/wiki/Opioid_use_disorder

    Long-term opioid use occurs in about 4% of people following their use for trauma or surgery-related pain. [20] In the United States, most heroin users begin by using prescription opioids that may also be bought illegally. [21] [22] People with opioid use disorder are often treated with opioid replacement therapy using methadone or buprenorphine ...

  6. Opioid overdose - Wikipedia

    en.wikipedia.org/wiki/Opioid_overdose

    Opiate overdose symptoms and signs can be referred to as the "opioid toxidrome triad": decreased level of consciousness, pinpoint pupils and respiratory depression. Other symptoms include seizures and muscle spasms. Sometimes an opiate overdose can lead to such a decreased level of consciousness such that the person will not wake up.

  7. Recreational drug use - Wikipedia

    en.wikipedia.org/wiki/Recreational_drug_use

    Opiates and opioids: Available by prescription for pain relief. Commonly used opioids include oxycodone, hydrocodone, codeine, fentanyl, heroin, methadone, and morphine. Opioids have a high potential for addiction and have the ability to induce severe physical withdrawal symptoms upon cessation of frequent use.

  8. Benzodiazepine use disorder - Wikipedia

    en.wikipedia.org/wiki/Benzodiazepine_use_disorder

    Benzodiazepine abuse is mostly limited to individuals who abuse other drugs, i.e. poly-drug abusers. Most prescribed users do not abuse their medication, however, some high dose prescribed users do become involved with the illicit drug scene. Abuse of benzodiazepines occurs in a wide age range of people and includes teenagers and the old.

  9. Fentanyl - Wikipedia

    en.wikipedia.org/wiki/Fentanyl

    Meperidine is a fully synthetic opioid, and other members of the phenylpiperidine family like alfentanil and sufentanil are complex versions of this structure. [71] Like other opioids, fentanyl is a weak base that is highly lipid-soluble, protein-bound, and protonated at physiological pH. [71]