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Septic shock is a result of a systemic response to infection or multiple infectious causes. The precipitating infections that may lead to septic shock if severe enough include but are not limited to appendicitis, pneumonia, bacteremia, diverticulitis, pyelonephritis, meningitis, pancreatitis, necrotizing fasciitis, MRSA and mesenteric ischemia.
Infection is generally associated with breaks in the skin or mucosal membranes due to surgery, injury, or use of intravascular devices such as cannulas, hemodialysis machines, or hypodermic needles. [ 3 ] [ 44 ] Once the bacteria have entered the bloodstream, they can infect various organs, causing infective endocarditis , septic arthritis ...
The infection can be life-threatening. Problematically, methicillin-resistant Staphylococcus aureus (MRSA) has become a major cause of hospital-acquired infections. MRSA has also been recognized with increasing frequency in community-acquired infections. [7] The symptoms of a staphylococcal infection include a collection of pus, such as a boil ...
However, along with similar bacterial species that can colonize and act symbiotically, they can cause disease if they begin to take over the tissues they have colonized or invade other tissues; the resultant infection has been called a "pathobiont". [2] After 72 hours, MRSA can take hold in human tissues and eventually become resistant to ...
Severe sepsis causes poor organ function or blood flow. [9] The presence of low blood pressure, high blood lactate, or low urine output may suggest poor blood flow. [9] Septic shock is low blood pressure due to sepsis that does not improve after fluid replacement. [9] Sepsis is caused by many organisms including bacteria, viruses, and fungi. [10]
Salmonella is a genus of bacteria, known to cause gastrointestinal infections. [15] Staphylococcus aureus is a bacterium known to cause skin infections and sepsis, among other pathologies. Notably, S. aureus has evolved several drug-resistant strains, including MRSA. [16] [17] Streptococcus pneumoniae is a bacterium that causes respiratory ...
Streptococcal infections include sepsis, pneumonia, and meningitis. [8] These infections can become serious creating a systemic inflammatory response resulting in massive vasodilation, shock, and death. [9] Other bacteria are opportunistic pathogens and cause disease mainly in people with immunosuppression or cystic fibrosis.
Bloodstream infections (BSIs) are infections of blood caused by blood-borne pathogens. [1] The detection of microbes in the blood (most commonly accomplished by blood cultures [2]) is always abnormal. A bloodstream infection is different from sepsis, which is characterized by severe inflammatory or immune responses of the host organism to ...