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Decoy cells are virally infected epithelial cells that can be found in the urine. Decoy cells owe their name to their strong resemblance to cancer cells, and may as such confuse the diagnosis of either viral infection or urothelial malignancy. During 1950s, cytotechnologist Andrew Ricci observed cells mimicking cancer cells by they were not, in ...
Polyomaviridae is a family of viruses whose natural hosts are primarily mammals and birds. [1] [2] As of 2024, there are eight recognized genera. [3]Fourteen species are known to infect humans, while others, such as Simian Virus 40, have been identified in humans to a lesser extent.
Human polyomavirus 2 may also be a causative agent of aseptic meningitis (JCVM), as Human polyomavirus 2 was the only pathogen identified in the CSF of certain patients with meningitis. Analysis of the JCVM variant revealed archetype-like regulatory regions with no mutations in coding sequences.
The BK virus, also known as Human polyomavirus 1, is a member of the polyomavirus family. Past infection with the BK virus is widespread, [1] but significant consequences of infection are uncommon, with the exception of the immunocompromised and the immunosuppressed. BK virus is an abbreviation of the name of the first patient, from whom the ...
The primary alphapolyomavirus that is of clinical significance to humans is Merkel cell polyomavirus (Human polyomavirus 5, MCV, or MCPyV). The apparent oncogenicity of MCPyV [ 6 ] similar to other cancer-causing viruses such as HPV , Epstein-Barr virus , and Hepatitis C virus [ 7 ] is a main area of research for the scientific community.
All known human polyomaviruses are fairly common in healthy adult populations and are usually asymptomatic. In studies that profile polyomavirus seroprevalence, or prevalence of detectable antibodies against viral proteins indicating either past or present exposure in immunocompetent adults, HPyV9 tends to have a relatively lower prevalence compared to other human polyomaviruses.
All known human polyomaviruses are fairly common in healthy adult populations and are usually asymptomatic. In studies that profile polyomavirus seroprevalence, or prevalence of detectable antibodies against viral proteins indicating either past or present exposure in immunocompetent adults, estimates of HPyV6 prevalence have ranged from approximately 60–85%, with evidence of low prevalence ...
The first group to publish gave the virus the "Malawi" designation based on the geographic location of the index case, a healthy child from Malawi; the designation "MW polyomavirus" has been included in the International Committee on Taxonomy of Viruses proposed classification of polyomaviruses. It was the 10th human polyomavirus to be ...