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  2. Vaso-occlusive crisis - Wikipedia

    en.wikipedia.org/wiki/Vaso-occlusive_crisis

    A vaso-occlusive crisis is a common painful complication of sickle cell anemia in adolescents and adults. [1] [2] It is a form of sickle cell crisis.Sickle cell anemia – most common in those of African, Hispanic, and Mediterranean origin – leads to sickle cell crisis when the circulation of blood vessels is obstructed by sickled red blood cells, causing ischemic injuries.

  3. Acute chest syndrome - Wikipedia

    en.wikipedia.org/wiki/Acute_chest_syndrome

    The acute chest syndrome is a vaso-occlusive crisis of the pulmonary vasculature commonly seen in people with sickle cell anemia. This condition commonly manifests with a new opacification of the lung(s) on a chest x-ray. [1]

  4. Splenic sequestration crisis - Wikipedia

    en.wikipedia.org/wiki/Splenic_sequestration_crisis

    Up to 30% of these children may develop splenic sequestration crisis with a mortality rate of up to 15%. This crisis occurs when splenic vaso-occlusion causes a large percentage of total blood volume to become trapped within the spleen. Clinical signs include severe, rapid drop in hemoglobin leading to hypovolemic shock and death.

  5. FDA panel says Vertex/CRISPR to assess safety risks of gene ...

    www.aol.com/news/fda-panel-says-vertex-crispr...

    If the therapy is approved, Vertex has proposed a 15-year follow up of patients to evaluate the safety outcomes of the therapy. A vaso-occlusive crisis occurs when sickled red blood cells block ...

  6. Sickle cell disease - Wikipedia

    en.wikipedia.org/wiki/Sickle_cell_disease

    After sickling crisis (see above) it is the second-most common cause of hospitalization and it accounts for about 25% of deaths in patients with SCD. Most cases present with vaso-occlusive crises, and then develop acute chest syndrome. [31] [32]

  7. Toddler who has just days to live evacuated from Gaza for ...

    www.aol.com/toddler-just-days-live-evacuated...

    A Palestinian toddler who doctors say only has days to live without urgent medical treatment was evacuated from Gaza by the Jordanian military on Monday, in a special mission after Israel had ...

  8. Her 3-Year-Old Died of Invasive Strep A. Now She's Educating ...

    www.aol.com/her-3-old-died-invasive-222502821.html

    A rare but potentially fatal condition struck one family without warning during a vacation to Germany two years ago. And now, a heartbroken mom has gone viral on TikTok, opening up about losing ...

  9. Fetal hemoglobin - Wikipedia

    en.wikipedia.org/wiki/Fetal_hemoglobin

    This leads to the so-called vaso-occlusive crisis, which is a hallmark of the disease. [37] If fetal hemoglobin remains relatively high after birth, the number of painful episodes decreases in patients with sickle-cell disease and they have a better prognosis. [38]