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Type A: augmented pharmacological effects, which are dose-dependent and predictable [5]; Type A reactions, which constitute approximately 80% of adverse drug reactions, are usually a consequence of the drug's primary pharmacological effect (e.g., bleeding when using the anticoagulant warfarin) or a low therapeutic index of the drug (e.g., nausea from digoxin), and they are therefore predictable.
This is a general list of long-term side effects associated with Antipsychotic (neuroleptic) medication.. Many patients will not develop these side effects, although there is still a significant possibility of risks associated with Antipsychotic usage.
Lithium is thought to provide long-term mood stabilization and have anti-manic properties by modulating glutamate levels. [119] It is proposed that lithium competes with magnesium for binding to NMDA glutamate receptor , increasing the availability of glutamate in post-synaptic neurons , leading to a homeostatic increase in glutamate re-uptake ...
There is no evidence of greater liver function changes with higher doses of bicalutamide, and hence the liver toxicity of bicalutamide is not currently known to be dose-dependent across its clinically used dosage range. [164] Older age, for a variety of reasons, appears to be an important risk factor for drug-induced hepatotoxicity.
Mercury poisoning is a type of metal poisoning due to exposure to mercury. [3] Symptoms depend upon the type, dose, method, and duration of exposure. [3] [4] They may include muscle weakness, poor coordination, numbness in the hands and feet, skin rashes, anxiety, memory problems, trouble speaking, trouble hearing, or trouble seeing. [1]
In 1989, in a 4- to 6-year follow-up study of 30 inpatient people who used benzodiazepines non-medically, Neuropsychological function was found to be permanently affected in some people with long-term high dose non-medical use of benzodiazepines. Brain damage similar to alcoholic brain damage was observed.
Experts are urging those who take certain medications, including those used to treat high blood pressure, allergies, and mental health conditions, to take extra precautions during extreme heat ...
The major treatments are removal of the source of lead and the use of medications that bind lead so it can be eliminated from the body, known as chelation therapy. [4] Chelation therapy in children is recommended when blood levels are greater than 40–45 μg/dL. [4] [12] Medications used include dimercaprol, edetate calcium disodium, and ...