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Magnetic resonance image of PNET. Most children that develop primitive neuroectodermal tumors are diagnosed early in life, usually at around 3–6.8 years of age. [2] Symptoms patients present at time of diagnosis include irritable mood, visual difficulties, lethargy, and ataxia. [2]
Because symptoms are non-specific, diagnosis is often delayed. [ 18 ] Measurement of hormones including pancreatic polypeptide , gastrin , proinsulin , insulin , glucagon , and vasoactive intestinal peptide can determine if a tumor is causing hypersecretion.
Children are much more prone to exhibit these dysembryoplastic neuroepithelial tumours than adults. [1] The mean age of onset of seizures for children with DNTs is 8.1 years old. [ 1 ] Few other neurological deficits are associated with DNTs, so that earlier detection of the tumour before seizure symptoms are rare. [ 2 ]
Symptomatic features of paraneoplastic syndrome cultivate in four ways: endocrine, neurological, mucocutaneous, and hematological.The most common presentation is a fever (release of endogenous pyrogens often related to lymphokines or tissue pyrogens), but the overall picture will often include several clinical cases observed which may specifically simulate more common benign conditions.
Central pontine myelinolysis is a neurological condition involving severe damage to the myelin sheath of nerve cells in the pons (an area of the brainstem). It is predominately iatrogenic (treatment-induced), and is characterized by acute paralysis, dysphagia (difficulty swallowing), dysarthria (difficulty speaking), and other neurological symptoms.
People often have few or no symptoms. [1] They may get occasional muscular weakness, muscle spasms, tingling sensations, or excessive urination. [1] High blood pressure, manifestations of muscle cramps (due to hyperexcitability of neurons secondary to low blood calcium), muscle weakness (due to hypoexcitability of skeletal muscles secondary to hypokalemia), and headaches (due to low blood ...
PNET may refer to: Peaceful Nuclear Explosions Treaty; Primitive neuroectodermal tumor; Pancreatic neuroendocrine tumor This page was last edited on 20 ...
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