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In September 2024, it was approved for medical use in the United States. [ 1 ] [ 2 ] It is the first antipsychotic drug approved by the US Food and Drug Administration (FDA) to treat schizophrenia that targets cholinergic receptors as opposed to dopamine receptors , which has long been the standard of care.
Unlike other antipsychotics, pimavanserin is not a dopamine receptor antagonist, [5] but rather is a selective antagonist or inverse agonist of the serotonin 5-HT 2A receptor and to a lesser extent of the serotonin 5-HT 2C receptor. [3] Pimavanserin was first approved for medical use in 2016. [3] It was approved as a generic medication in 2024. [6]
It was approved for medical use in the United States in July 2015. [16] [17] A generic version was approved in August 2022. [18] Brexpiprazole is the first treatment approved by the US Food and Drug Administration (FDA) for agitation associated with dementia due to Alzheimer's disease. [13]
The 15 drugs accounted for $41 billion, or 14%, of total Medicare Part D spending between Nov. 1, 2023, and Oct. 1, 2024.
Samidorphan (INN Tooltip International Nonproprietary Name, USAN Tooltip United States Adopted Name) is an opioid antagonist that in the form of olanzapine/samidorphan (sold as Lybalvi) is used in the treatment of schizophrenia and bipolar disorder.
The U.S. Food and Drug Administration expanded approval for Johnson & Johnson’s nasal spray, Spravato, to allow it to be used as a standalone treatment for patients with severe depression, the ...
Tiotixene, or thiothixene is a typical antipsychotic agent currently sold under the brand name Navane which is predominantly utilised to treat acute and chronic schizophrenia. [2] Beyond its primary indication , it can exhibit a variety of effects common to neuroleptic drugs including anxiolytic , anti-depressive, and anti-aggressive properties.
A new type of non-opioid painkiller, aimed at treating short-term pain in adults, has been approved by the US Food and Drug Administration (FDA). The drug suzetrigine, known by its brand name ...
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