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Acceptable daily intake or ADI is a measure of the amount of a specific substance (originally applied for a food additive, later also for a residue of a veterinary drug or pesticide) in food or drinking water that can be ingested (orally) daily over a lifetime without an appreciable health risk. [1]
A 12-US-fluid-ounce (350 ml; 12 imp fl oz) can of diet soda contains 0.18 grams (0.0063 oz) of aspartame, and, for a 75-kilogram (165 lb) adult, it takes approximately 21 cans of diet soda daily to consume the 3.7 grams (0.13 oz) of aspartame that would surpass the FDA's 50 mg/kg of body weight ADI of aspartame from diet soda alone.
In the United States, six high-intensity sugar substitutes have been approved for use: aspartame, sucralose, neotame, acesulfame potassium (Ace-K), saccharin and advantame. [3] Food additives must be approved by the FDA, [ 3 ] and sweeteners must be proven as safe via submission by a manufacturer of a GRAS document. [ 44 ]
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Mice on the aspartame diet had persistently high insulin levels, suggesting that long-term consumption of this artificial sweetener may lead to insulin resistance, which greatly increases the risk ...
The only exception is aspartame, which provides the same amount of calories as sugar per gram but is typically used in small quantities. Sugar alcohols. Sugar alcohols include erythritol, xylitol ...
The artificial sweetener aspartame has been the subject of several controversies since its initial approval by the U.S. Food and Drug Administration (FDA) in 1974. The FDA approval of aspartame was highly contested, beginning with suspicions of its involvement in brain cancer, [1] alleging that the quality of the initial research supporting its safety was inadequate and flawed, and that ...
Because aspartame is about 200 times sweeter than sugar, the amount of aspartame needed to sweeten one 12-ounce can of diet soda is very small — only about 192 milligrams, or 0.007 ounces. How ...