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The Quality of Life of Carers of Alzheimer's Disease Patients (ACQLI) is a measure which assesses the quality of life of people who care for Alzheimer's disease patients. It was developed in 1997 by Galen Research [1] and has been used in studies investigating rosiglitazone [2] [3] [4] and the effects of pharmacological treatment. [5] Angina.
Theophylline's first clinical use came in 1902 as a diuretic. [35] It took an additional 20 years until it was first reported as an asthma treatment. [ 36 ] The drug was prescribed in a syrup up to the 1970s as Theostat 20 and Theostat 80, and by the early 1980s in a tablet form called Quibron.
This is an accepted version of this page This is the latest accepted revision, reviewed on 1 March 2025. Long-term brain disorders causing impaired memory, thinking and behavior This article is about the cognitive disorder. For other uses, see Dementia (disambiguation). "Senile" and "Demented" redirect here. For other uses, see Senile (disambiguation) and Demented (disambiguation). Medical ...
Later research found that the combination was no more effective for asthma than theophylline alone but produced more side effects. [9] [1] [12] [7] Combinations of theophylline, ephedrine, and phenobarbital (brand name Tedral among others) have also been widely used to treat asthma.
In animal and human studies, it has shown similar efficacy to theophylline but with significantly fewer side effects. [5] In February 2014, the US FDA granted an orphan drug designation to doxofylline for the treatment of bronchiectasis following the submission of an application by Alitair Pharmaceuticals, in May 2013. [6] [7] [8]
Aminophylline is a compound of the bronchodilator theophylline with ethylenediamine in 2:1 ratio. The ethylenediamine improves solubility, and the aminophylline is usually found as a dihydrate. [2] Aminophylline is less potent and shorter-acting than theophylline. Its most common use is in the treatment of airway obstruction from asthma or COPD.
Diphenhydramine is the primary constituent of dimenhydrinate and dictates the primary effect. The main differences relative to pure diphenhydramine are a lower potency due to being combined with 8-chlorotheophylline (by weight, dimenhydrinate is between 53% and 55.5% diphenhydramine) [10] and the fact that the stimulant properties of 8-chlorotheophylline help reduce the side ...
Nevertheless, as important as these effects are, the main support for the use of stimulation therapies is improvement in the patient's daily life routines. [10] A study published in 2006 tested the effects of cognitive stimulation therapy (CST) on the demented elderly's quality of life. The researchers looked at the effect of CST on cognitive ...