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Phenylbiguanide (PBG) is a 5-HT3 agonist used to study the role of 5-HT3 receptors in the central nervous system. [1] It has been found to trigger dopamine release in the nucleus accumbens of rats. [ 2 ]
Biguanide (/ b aɪ ˈ ɡ w ɒ n aɪ d /) is the organic compound with the formula HN(C(NH)NH 2) 2. It is a colorless solid that dissolves in water to give a highly basic solution. It is a colorless solid that dissolves in water to give a highly basic solution.
[1] [2] [7] For comparison, the affinities of LSD and DOM in the same study were 6.31 nM and 18.6 nM, respectively. [7] DOSB substitutes for LSD in rodent drug discrimination tests, albeit much less potently than DOM ( ED 50 Tooltip median effective dose = 1.80 mg/kg versus 0.148 mg/kg, respectively; ~12-fold difference) and with only partial ...
En toutes lettres (2009-2011) Et 1, et 2, et 3 ! (1999) Face à ... Informations and programs at programmes.france2.fr [in French ... List of programs broadcast by ...
meta-Chlorophenylbiguanide (1-(3-Chlorophenylbiguanide, m-CPBG) is an allosteric agonist and modulator of the 5-HT 3 receptor [1] [2] [3] and an antagonist of the α 2A-adrenergic receptor. [4] It has anxiogenic , emetic and hypothermic effects in animal studies.
BMB-201 is a serotonin 5-HT 2A and 5-HT 2C receptor agonist described as a non-hallucinogenic psychoplastogen which is under development for the treatment of depression, anxiety, pain, and other indications.
VU0530244 is a potent, selective, and putatively peripherally restricted serotonin 5-HT 2B receptor antagonist which was first described in 2023. [1] [2] [3] Another similar drug, VU0631019, was also described alongside VU0530244. [3]
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