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UniProtKB/Swiss-Prot is a manually annotated, non-redundant protein sequence database. It combines information extracted from scientific literature and biocurator-evaluated computational analysis. The aim of UniProtKB/Swiss-Prot is to provide all known relevant information about a particular protein.
Swiss-Prot has collected over 81 000 variants in roughly 13,000 human protein sequence records from peer-reviewed literature. It is unclear how many unique proteins types are present in the database. Signal transduction pathway databases
BAR 3.0 is a server for the annotation of protein sequences relying on a comparative large-scale analysis on the entire UniProt. With BAR 3.0 and a sequence you can annotate when possible: function (Gene Ontology), structure (Protein Data Bank), protein domains (Pfam).
a protein databases that includes visuals of protein structure. Also, includes protein pathways and gene sequences including other tools. SCOP the Structural Classification of Proteins a detailed and comprehensive description of the structural and evolutionary relationships between all proteins whose structure is known. SWISS-MODEL Repository a ...
The institute was originally created to provide a framework for stable long-term funding for both the Swiss-Prot database and the Swiss EMBnet node. Swiss-Prot in particular went through a major funding crisis in 1996, [1] which led the leaders of the five research groups active in bioinformatics in Geneva and Lausanne, Ron Appel, Amos Bairoch, Philipp Bucher, Victor Jongeneel and Manuel ...
Gasteiger's work at the Swiss Institute of Bioinformatics (SIB) has been instrumental in the development and enhancement of key bioinformatics resources, including the UniProt database, an integrated platform that combines protein sequence data from Swiss-Prot, TrEMBL, and PIR, as well as the ExPASy platform, which provides a suite of tools to support protein sequence analysis and related ...
In 2002, PIR – along with its international partners, the European Bioinformatics Institute and the Swiss Institute of Bioinformatics – were awarded a grant from NIH to create UniProt, a single worldwide database of protein sequence and function, by unifying the Protein Information Resource-Protein Sequence Database, Swiss-Prot, and TrEMBL ...
The UniProt database is an example of a protein sequence database. As of 2013 it contained over 40 million sequences and is growing at an exponential rate. [ 1 ] Historically, sequences were published in paper form, but as the number of sequences grew, this storage method became unsustainable.