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The exact mechanism of HIV-associated lipodystrophy is not fully elucidated. There is evidence indicating both that it can be caused by anti-retroviral medications and that it can be caused by HIV infection in the absence of anti-retroviral medication.
Kaposi's Sarcoma (KS) is an extremely common disease that arises in AIDS patients and HIV-infected individuals. The condition is characterized by large purple lesions on the skin and mouth. KS presents itself differently for everyone affected by it, and its symptoms and progression varies from person to person as well. [5]
Lipodystrophy can be a possible side effect of certain antiretroviral drugs. Lipoatrophy is most commonly seen in patients treated with thymidine analogues and other older HIV drug treatments such as the nucleoside reverse transcriptase inhibitors [NRTIs] [9] like zidovudine (AZT) and stavudine (d4T). [10]
Lipoatrophy occurs in HIV-associated lipodystrophy, one cause of which is an adverse drug reaction that is associated with some antiretroviral medications. [2] A more general term for an abnormal or degenerative condition of the entire body's adipose tissue is lipodystrophy.
Drug-induced lipodystrophy; Factitial panniculitis; Familial partial lipodystrophy (Köbberling–Dunnigan syndrome) Gouty panniculitis; Hemihyperplasia–multiple lipomatosis syndrome; HIV-associated lipodystrophy [nb 8] Involutional lipoatrophy; Lipoatrophia annularis (Ferreira–Marques lipoatrophia) Lipoatrophia semicircularis (semicircular ...
Drug-induced lipodystrophy is a cutaneous condition that presents as one or multiple depressed areas (i.e. indentations), usually on the proximal extremities, ranging from under a few centimeters to greater than 20 centimetres (7.9 in) in diameter.
Figure 1. Early Symptoms of HIV. The stages of HIV infection are acute infection (also known as primary infection), latency, and AIDS. Acute infection lasts for several weeks and may include symptoms such as fever, swollen lymph nodes, inflammation of the throat, rash, muscle pain, malaise, and mouth and esophageal sores. The latency stage ...
Wasting syndrome in the absence of a concurrent illness other than HIV infection that could explain the following findings: a) persistent weight loss more than 10% of baseline OR b) downward crossing of at least two of the following percentile lines on the weight-for-age chart (e.g., 95th, 75th, 50th, 25th, 5th) in a child at least 1 year of ...