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Helminthiasis, also known as worm infection, is any macroparasitic disease of humans and other animals in which a part of the body is infected with parasitic worms, known as helminths. There are numerous species of these parasites , which are broadly classified into tapeworms , flukes , and roundworms .
Praziquantel (PZQ), sold under the brandname Biltricide among others, is a medication used to treat a number of types of parasitic worm infections in mammals, birds, amphibians, reptiles, and fish. [3]
The two drugs that have been well-described for the treatment of hymenolepiasis are praziquantel and niclosamide. Praziquantel, which is parasiticidal in a single dose for all the stages of the parasite, is the drug of choice because it acts very rapidly against H. nana. Although structurally unrelated to other anthelminthics, it kills both ...
Praziquantel can be administered to kill adult schistosomes and prevent chronic infection in addition to corticosteroid therapy. [19] It is ineffective for recent infections as it only targets adult worms rather than premature schistosomulae. [25] Therefore, a repeat praziquantel treatment several weeks after initial infection may be warranted ...
This therapy ties to the Hygiene hypothesis in that the lack of exposure to bacteria and parasites such as helminths can cause a weaker immune system leading to being more susceptible to autoimmune disease. [4] [5] Helminth worms are members of two phyla: nematodes, which are primarily used in human helminthic therapy, and flat worms . [2]
This is a particularly serious problem in helminth parasites of small ruminant farm animals. [12] There are many factors that contribute to anthelmintic resistance, such as frequent, mass anthelmintic treatment, underdosing, treating repeatedly with only one anthelmintic, and resistance being transmitted during transfer of animals. [12]
The prescription drug Praziquantel is usually prescribed in a single dose to patients infected with H.nana. Praziquantel is widely used and preferred due to its high efficacy. Research has shown that the cysticercoid phase of H.nana's life cycle is the most susceptible to the Praziquantel treatment. [2]
In some cases, the infection can lead to more severe complications such as intestinal obstruction or inflammation. Echinostomiasis is diagnosed by examining stool samples for the presence of adult worms or eggs. Treatment typically involves the use of anthelmintic medications such as praziquantel or albendazole.
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related to: praziquantel helminth infection treatment"The lowest prices on generic prescriptions." - The New York Times