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Metabolife International, Inc. was a multi-level marketing company based in San Diego, California which manufactured dietary supplements.Metabolife's best-selling product, an ephedra supplement called Metabolife 356, once generated hundreds of millions of dollars in annual sales. [1]
Chemins was the manufacturer of dietary supplements for the multi-level marketing companies Metabolife (i.e., Metabolife 356, an ephedra-based supplement that was withdrawn following numerous adverse event reports) [4] [5] and LifeVantage (i.e., Protandim, an herbal-based supplement). [6] Chemins' assets were acquired by Nexgen Pharma in 2007. [7]
Ephedra is a genus of gymnosperm shrubs.As of February 2025 there were 77 recognized species. The various species of Ephedra are widespread in many arid regions of the world, ranging across southwestern North America, southern Europe, northern Africa, southwest and central Asia, northern China, and western South America. [2]
A wide variety of alkaloid and non-alkaloid compounds have been identified in various species of Ephedra.Of the six ephedrine-type ingredients found in ephedra (at concentrations of 0.02-3.4%), the most common are ephedrine and pseudoephedrine, [13] which are the sources of its stimulant and thermogenic effects. [4]
95 characters; the 52 alphabet characters belong to the Latin script. The remaining 43 belong to the common script. The 33 characters classified as ASCII Punctuation & Symbols are also sometimes referred to as ASCII special characters. Often only these characters (and not other Unicode punctuation) are what is meant when an organization says a ...
special characters that are not available in the limited character set are stored in the form of a multi-character code; there are usually two or three equivalent representations, e.g. for the character € the named character reference € and the decimal character reference € and the hexadecimal character reference €. The edit ...
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Cotinine has an in vivo half-life of approximately 20 hours, and is typically detectable for several days (up to one week) after the use of tobacco. The level of cotinine in the blood, saliva, and urine is proportionate to the amount of exposure to tobacco smoke, so it is a valuable indicator of tobacco smoke exposure, including secondary (passive) smoke. [14]