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Drug-induced glomerular disease is not common but there are a few drugs that have been implicated. Glomerular lesions occur primarily through immune-mediated pathways rather than through direct drug toxicity. Heroin and Pamidronate are known to cause focal segmental glomerulosclerosis; Gold salts therapy can cause membranous nephropathy [4 ...
Levofloxacin, sold under the brand name Levaquin among others, is a broad-spectrum antibiotic of the fluoroquinolone drug class. [6] It is the left-handed isomer of the medication ofloxacin .
Kidney disease can affect drug elimination, absorption, and distribution in the body, leading to altered serum drug concentrations. This can increase the risk of drug toxicity or suboptimal therapeutic effects. As a result, dosage adjustments are necessary for patients who fail to achieve the desired therapeutic serum drug levels. [27]
AKI - the other main type of kidney disease - can be caused by dehydration, blood loss, urinary tract obstructions such as kidney stones or blood clots, low blood pressure, or heart disease. It ...
[4] [6] Those with severe disease may require treatment in hospital. [2] In those with certain structural problems of the urinary tract or kidney stones, surgery may be required. [1] [3] Pyelonephritis affects about 1 to 2 per 1,000 women each year and just under 0.5 per 1,000 males.
A kidney infection during pregnancy may result in preterm birth or pre-eclampsia (a state of high blood pressure and kidney dysfunction during pregnancy that can lead to seizures). [42] Some women have UTIs that keep coming back in pregnancy. [112] There is insufficient research on how to best treat these recurrent infections. [112]
Membranous glomerulonephritis, the most common cause for nephrotic syndrome in adults, peaks in people ages 40–60 years old and it is twice as likely to occur in men than in women. Since nephrotic syndrome is the most common cause of RVT, people over 40 years old and men are most at risk to develop a renal vein thrombosis. [3]
IgA nephropathy. This is a condition in which small amount of a type of normal antibody (called IgA) get stuck in the kidney as it passes through in the bloodstream. This is a chronic condition, which sometimes goes away on its own but occasionally can cause damage to the kidneys. A related condition called IgM nephropathy can sometimes cause pain.
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