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Cefadroxil is a first-generation cephalosporin antibacterial drug that is the para-hydroxy derivative of cephalexin, and is used similarly in the treatment of mild to moderate susceptible infections such as the bacterium Streptococcus pyogenes, causing the disease popularly called strep throat or streptococcal tonsillitis, urinary tract infection, reproductive tract infection, and skin infections.
Cefalexin is the International Nonproprietary Name (INN) and the Australian Approved Name (AAN), while cephalexin is the British Approved Name (BAN) and the United States Adopted Name (USAN). [33] Brand names for cefalexin include Keflex, Acfex, Cephalex, Ceporex, L-Xahl, Medoxine, Ospexin, Torlasporin, Bio-Cef, Panixine DisperDose, and Novo-Lexin.
Guanosine-5'-triphosphate (GTP) is a purine nucleoside triphosphate. It is one of the building blocks needed for the synthesis of RNA during the transcription process. Its structure is similar to that of the guanosine nucleoside , the only difference being that nucleotides like GTP have phosphates on their ribose sugar.
Cefradine is distributed in the form of capsules containing 250 mg or 500 mg, as a syrup containing 250 mg/5 ml, or in vials for injection containing 500 mg or 1 g. [citation needed] It is not approved by the FDA for use in the United States. [citation needed]
Tuinal was the brand name of a discontinued combination drug composed of two barbiturate sodium salts (secobarbital and amobarbital) in equal proportions.. Tuinal was introduced as a sedative-hypnotic (sleeping pill) medication in the late 1940s by Eli Lilly.
In enzymology, a GTP diphosphokinase (EC 2.7.6.5) is an enzyme that catalyzes the chemical reaction ATP + GTP ⇌ {\displaystyle \rightleftharpoons } AMP + guanosine 3'-diphosphate 5'-triphosphate Thus, the two substrates of this enzyme are ATP and GTP , whereas its two products are AMP and guanosine 3'-diphosphate 5'-triphosphate .
Hydrolysis of GTP bound to an (active) G domain-GTPase leads to deactivation of the signaling/timer function of the enzyme. [2] [3] The hydrolysis of the third (γ) phosphate of GTP to create guanosine diphosphate (GDP) and P i, inorganic phosphate, occurs by the S N 2 mechanism (see nucleophilic substitution) via a pentacoordinate transition state and is dependent on the presence of a ...
In enzymology, a GTP cyclohydrolase II (EC 3.5.4.25) is an enzyme that catalyzes the chemical reaction GTP + 3 H 2 O ⇌ {\displaystyle \rightleftharpoons } formate + 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine + diphosphate