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[8] [9] The time between exposure to the virus and development of symptoms (the incubation period) is one to four days, most commonly one to two days. Many infections are asymptomatic. [ 10 ] The onset of symptoms is sudden, and initial symptoms are predominately non-specific, including fever, chills, headaches, muscle pain , malaise , loss of ...
The time between symptom onset and death ranges from 6 to 41 days, typically about 14 days. [81] Mortality rates increase as a function of age. People at the greatest mortality risk are the elderly and those with underlying conditions.
This measure of sickness is contrasted with the mortality rate of a condition, which is the proportion of people dying during a given time interval. Morbidity rates are used in actuarial professions, such as health insurance, life insurance, and long-term care insurance, to determine the premiums charged to customers.
The most common cause of death is respiratory failure. Other causes of death are pneumonia (leading to sepsis), [17] high fever (leading to neurological problems), dehydration (from excessive vomiting and diarrhea), electrolyte imbalance and kidney failure. [18] Fatalities are more likely in young children and the elderly.
In 1918, older adults may have had partial protection caused by exposure to the 1889–1890 flu pandemic, known as the "Russian flu". [301] According to historian John M. Barry, the most vulnerable of all – "those most likely, of the most likely", to die – were pregnant women.
In 2000, 1.7 million (1.8%) African children living in areas of the world where malaria is common were protected by an ITN. That number increased to 20.3 million (18.5%) African children using ITNs in 2007, leaving 89.6 million children unprotected [95] and to 68% African children using mosquito nets in 2015. [96]
A 2017 study, using records of more than 35,000 patients, also found average temperature at nearly 97.9 degrees. Women have higher temperatures than men, and older people are usually colder.
[43] [81] On 27 February 1950, Koprowski's live, attenuated vaccine was tested for the first time on an 8-year-old boy living at Letchworth Village, an institution for physically and mentally disabled people located in New York. After the child had no side effects, Koprowski enlarged his experiment to include 19 other children.