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The exposome is a concept used to describe environmental exposures that an individual encounters throughout life, and how these exposures impact biology and health. It encompasses both external and internal factors, including chemical, physical, biological, and social factors that may influence human health.
Exosomes were first discovered in the maturing mammalian reticulocyte (immature red blood cell) by Stahl and group in 1983 [16] and Johnstone and group in 1983 [17] further termed 'exosomes' by Johnstone and group in 1987. [18]
Exposome (2005) Exposomics: An individual's environmental exposures, including in the prenatal environment: Molecular genetics: A proposed term and field of study of the disease-causing effects of environmental factors (the "nurture" component of "nature vs. nurture"). [5] Exposome (2009) Composite occupational exposures and occupational health ...
Exposome. In late 2013, this definition was explained in greater depth in the first book on the exposome. [18] [19] In 2014, the same author revised the definition to include the body's response with its endogenous metabolic processes which alter the processing of chemicals. [14]
What we eat and how we live impact our gene expression and cellular biology, determining our outcomes. Food chemicals go into your body and act as signaling molecules. They can directly increase ...
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Adducts may arise as a consequence of the chemical reaction between a given "physicochemical agent to which an organism is exposed across the lifespan" (sometimes referred to as the exposome). These physicochemical agents can be exogenous in origin, and include ionizing and non-ionizing radiation, the diet, lifestyle factors, pollution, and ...
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