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Human skin is a very impermeable membrane that protects the body from ingress of harmful substances and prevents water loss from underlying organs. However, this seriously limits the use of skin as a site for drug administration. One of the approaches to facilitate transdermal drug delivery is the use of penetration enhancers. Many different ...
The peptides inside mimic the those within the skin to keep the eye area plump and smooth. In true Skinceuticals fashion, it also offers a host of other benefits, like fighting dark circles and ...
Cell-penetrating peptide facilitated translocation is a topic of great debate. Evidence has been presented that translocation could use several different pathways for uptake. In addition, the mechanism of translocation can be dependent on whether the peptide is free or attached to cargo.
Marketing claims about peptides are often exaggerated as an anti-aging skin treatment.
There are a handful of skincare ingredients that you’ll find on the labels of many of your go-to products, including retinol , vitamin...
The blood–ocular barrier is a barrier created by endothelium of capillaries of the retina and iris, ciliary epithelium and retinal pigment epithelium. [1] It is a physical barrier between the local blood vessels and most parts of the eye itself, and stops many substances including drugs from traveling across it. [2]
Defensins are a type of antimicrobial peptide; and are an important component of virtually all innate host defenses against microbial invasion. Defensins penetrate microbial cell membranes by way of electrical attraction, and form a pore in the membrane allowing efflux, which ultimately leads to the lysis of microorganisms. [72] Neuronal peptides
Melanin is a chromophore that exists in the human epidermal layer of skin responsible for protection from harmful UV radiation. When melanocytes are stimulated by solar radiation, melanin is produced. [7] Melanin is one of the major absorbers of light in some biological tissue (although its contribution is smaller than other components).
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