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Rarely eosinophils [1] Allergic drug reaction Rarely involvement of hair follicles. [1] Frequently eosinophils [1] Lichen sclerosus: Hyperkeratosis, atrophic epidermis, sclerosis of dermis and dermal lymphocytes. [2] Erythema multiforme Lupus erythematosis Typical findings in systemic lupus erythematosus: [3] Fibrinoid necrosis at the ...
In non-bullous cases, perivascular and interstitial neutrophils are sometimes present in the upper dermis, with damage to blood vessels An interface dermatitis with vacuolar alteration, not otherwise specified, may be caused by viral exanthems , phototoxic dermatitis , acute radiation dermatitis , erythema dyschromicum perstans , lupus ...
Typically a superficial and deep perivascular lymphocytic infiltrate. [22] Plasma cells are typically located at the periphery of the lesion, whereas eosinophils are in the center. [22] Kaposi’s sarcoma in patch stage The patch stage typically shows irregular proliferation of jagged vascular channels in the dermis below an integral epidermis.
Eosinophilic dermatosis is a form of dermatosis characterized by a preponderance of eosinophils in the dermis or epidermis. [1] Although it does not always imply a specific etiology, it is still commonly used as a classification in dermatology when more information about the condition is not known.
Based on their causes, hypereosinophilias can be sorted into subtypes. However, cases of eosinophilia, which exhibit eosinophil counts between 500 and 1,500/μL, may fit the clinical criteria for, and thus be regarded as falling into, one of these hypereosinophilia categories: the cutoff of 1,500/μL between hypereosinophilia and eosinophilia is somewhat arbitrary.
Eosinophilic granulomatosis with polyangiitis consists of three stages, but not all patients develop all three stages or progress from one stage to the next in the same order; [7] whereas some patients may develop severe or life-threatening complications such as gastrointestinal involvement and heart disease, some patients are only mildly affected, e.g. with skin lesions and nasal polyps. [8]
Hypereosinophilic syndrome is a disease characterized by a persistently elevated eosinophil count (≥ 1500 eosinophils/mm³) in the blood for at least six months without any recognizable cause, with involvement of either the heart, nervous system, or bone marrow. [5]
The symptoms of DRESS syndrome usually begin 2 to 6 weeks but uncommonly up to 8–16 weeks after exposure to an offending drug. Symptoms generally include fever, an often itchy rash which may be morbilliform or consist mainly of macules or plaques, facial edema (i.e. swelling, which is a hallmark of the disease), enlarged and sometimes painful lymph nodes, and other symptoms due to ...