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The New England Journal of Medicine (NEJM) is a weekly medical journal published by the Massachusetts Medical Society. Founded in 1812, the journal is among the most prestigious peer-reviewed medical journals. [1] Its 2023 impact factor was 96.2, ranking it 2nd out of 168 journals in the category "Medicine, General & Internal". [2]
The letter reported on an examination of medical files of patients who had been hospitalized and treated with small doses of opioids.The authors concluded that of the 11,882 patients who received at least one narcotic drug, only four of them had developed a "reasonably well documented" addiction among patients who had no history of addiction.
To enter the drug treatment system, such as it is, requires a leap of faith. The system operates largely unmoved by the findings of medical science. Peer-reviewed data and evidence-based practices do not govern how rehabilitation facilities work. There are very few reassuring medical degrees adorning their walls.
A brief letter published in the New England Journal of Medicine (NEJM) in January 1980, titled "Addiction Rare in Patients Treated with Narcotics", generated much attention and changed this thinking. [66] [67] A group of researchers in Canada claim that the letter may have originated and contributed to the opioid crisis. [66]
The Institute of Medicine committee has defined CER as "the generation and synthesis of evidence that compares the benefits and harms of alternative methods to prevent, diagnose, treat, and monitor a clinical condition or to improve the delivery of care. The purpose of CER is to assist consumers, clinicians, purchasers, and policy makers to ...
The West of Scotland Coronary Prevention Study (also known as WOSCOPS) was a landmark [1] randomized controlled trial, published in 1995, that investigated the effects of pravastatin, a cholesterol-lowering drug, on primary prevention of coronary heart disease (CHD) in men with hypercholesterolemia.
Real-world evidence (RWE) in medicine is the clinical evidence regarding the usage and potential benefits or risks of a medical product derived from analysis of real-world data (RWD). RWE can be generated by different study designs or analyses, including but not limited to, randomized trials, including large simple trials, pragmatic trials, and ...
Rosemary Oil. A very common oil included in natural hair growth products, studies have noted the efficacy of rosemary in promoting hair growth. In one study, results showed that rosemary oil may ...