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Levetiracetam, sold under the brand name Keppra among others, is a novel antiepileptic drug [7] used to treat epilepsy. [8] It is used for partial-onset , myoclonic , or tonic–clonic seizures, [ 7 ] and is taken either by mouth as an immediate or extended release formulation or by injection into a vein .
In clinical practice, this means that it takes 4 to 5 times the half-life for a drug's serum concentration to reach steady state after regular dosing is started, stopped, or the dose changed. So, for example, digoxin has a half-life (or t 1 / 2 ) of 24–36 h; this means that a change in the dose will take the best part of a week to ...
In pharmacology, clearance is a pharmacokinetic parameter representing the efficiency of drug elimination. This is the rate of elimination of a substance divided by its concentration. [ 1 ] The parameter also indicates the theoretical volume of plasma from which a substance would be completely removed per unit time.
t 1/2 is the half-life time of the drug, which is the time needed for the plasma drug concentration to drop to its half Therefore, the amount of drug present in the body at time t A t {\displaystyle A_{t}} is;
The rate at which a drug enters into the body for oral and other extravascular routes. 0.693 h −1: Elimination half-life: The time required for the concentration of the drug to reach half of its original value.
A Catholic nun with the Sisters of Charity Institute in Milan was among 25 people arrested early Thursday morning for a litany of mafia-related crimes, including aiding and abetting extortion ...
In this situation it is generally uncommon to talk about half-life in the first place, but sometimes people will describe the decay in terms of its "first half-life", "second half-life", etc., where the first half-life is defined as the time required for decay from the initial value to 50%, the second half-life is from 50% to 25%, and so on.
Seven people have been arrested and charged in connection to an alleged social media drug ring at Rutgers University, New Jersey officials announced this week.