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Nitrogen is a constituent of every major pharmacological drug class, including antibiotics. Many drugs are mimics or prodrugs of natural nitrogen-containing signal molecules: for example, the organic nitrates nitroglycerin and nitroprusside control blood pressure by metabolising into nitric oxide.
A large fraction of the chemical elements that occur naturally on the Earth's surface are essential to the structure and metabolism of living things. Four of these elements (hydrogen, carbon, nitrogen, and oxygen) are essential to every living thing and collectively make up 99% of the mass of protoplasm. [1]
The nitrogen cycle is an important process in the ocean as well. While the overall cycle is similar, there are different players [40] and modes of transfer for nitrogen in the ocean. Nitrogen enters the water through the precipitation, runoff, or as N 2 from the atmosphere. Nitrogen cannot be utilized by phytoplankton as N
The chemical element nitrogen is one of the most abundant elements in the universe and can form many compounds. It can take several oxidation states; but the most common oxidation states are -3 and +3. Nitrogen can form nitride and nitrate ions. It also forms a part of nitric acid and nitrate salts.
Nitrate salts are found naturally on earth in arid environments as large deposits, particularly of nitratine, a major source of sodium nitrate. Nitrates are produced by a number of species of nitrifying bacteria in the natural environment using ammonia or urea as a source of nitrogen and source of free
Nitrogen-15 is frequently used in NMR (Nitrogen-15 NMR spectroscopy). Unlike the more abundant nitrogen-14, which has an integer nuclear spin and thus a quadrupole moment, 15 N has a fractional nuclear spin of one-half, which offers advantages for NMR such as narrower line width. Nitrogen-15 tracing is a technique used to study the nitrogen cycle.
It is an important source of nitrogen for living systems. Although atmospheric nitrogen abounds (more than 75%), few living creatures are capable of using atmospheric nitrogen in its diatomic form, N 2 gas. Therefore, nitrogen fixation is required for the synthesis of amino acids, which are the building blocks of protein. Some plants rely on ...
A method for nitrogen fixation was first described by Henry Cavendish in 1784 using electric arcs reacting nitrogen and oxygen in air. This method was implemented in the Birkeland–Eyde process of 1903. [67] The fixation of nitrogen by lightning is a very similar natural occurring process.