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Both Jarisch and Herxheimer observed reactions in patients with syphilis treated with mercury. The reaction was first seen following treatment in early and later stages of syphilis treated with Salvarsan, mercury, or antibiotics. Jarisch thought that the reaction was caused by a toxin released from the dying spirochetes. [11]
Penicillin is the most commonly used antibiotic to treat syphilis. Other options may be used if you are allergic to penicillin, or your doctor may recommend a regimen that will allow your body to ...
When used to treat syphilis a reaction known as Jarisch-Herxheimer may occur. [5] It is not recommended in those with a history of penicillin allergy or those with syphilis involving the nervous system. [5] [3] Use during pregnancy is generally safe. [3] It is in the penicillin and beta lactam class of medications and works via benzylpenicillin.
When used to treat syphilis a reaction known as Jarisch-Herxheimer may occur. [2] It is not recommended in those with a history of penicillin allergy or procaine allergy. [1] [2] Use during pregnancy and breastfeeding is relatively safe. [1] [2] Procaine benzylpenicillin is in the penicillin and beta lactam family of medications. [2]
The so-called delabeling of penicillin allergies, doctors say, would have major health impacts: faster and more effective treatments for people who have spent their lives avoiding penicillin and ...
Usually, the penicillin injection needs to be given a month before the end of a pregnancy for it to work. ... you want to identify them as having syphilis and treat them at that time,” he said.
Treatment of suspected congenital syphilis is with penicillin by injection; benzylpenicillin into vein, or procaine benzylpenicillin into muscle. [3] [10] During times of penicillin unavailability, ceftriaxone may be an alternative. [10] Where there is penicillin allergy, antimicrobial desensitisation is an option. [10] [12]
Without treatment, syphilis can spread to the brain, eye or ear, and in some severe cases, cause dementia, blindness or hearing loss. ... one injection of long-acting penicillin can cure the early ...
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