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Vitamin A status involves eye health via two separate functions. Retinal is an essential factor in rod cells and cone cells in the retina responding to light exposure by sending nerve signals to the brain. An early sign of vitamin A deficiency is night blindness. [6] Vitamin A in the form of retinoic acid is essential to normal epithelial cell ...
Xerophthalmia (from Ancient Greek xērós (ξηρός) meaning "dry" and ophthalmos (οφθαλμός) meaning "eye") is a medical condition in which the eye fails to produce tears. It may be caused by vitamin A deficiency, [1] which is sometimes used to describe that condition, although there may be other causes.
Keratomalacia is an eye disorder that results from vitamin A deficiency. Vitamin A is required to maintain specialized epithelia (such as in the cornea and conjunctiva ). The precise mechanism is still not known, but vitamin A is necessary for the maintenance of the specialized epithelial surfaces of the body.
A major cause of Bitot's spots is vitamin A deficiency (VAD). [4] Rarely, pellagra due to deficiency of vitamin B 3 (niacin) may also cause Bitot's spots. [5] They can also be caused by Colestyramine , which is a bile acid sequestrant which can reduce the absorption of fat soluble vitamins (Vitamins A, D, E, K)
Vitamin A supplementation of children under five who are at risk of VAD has been found to reduce all‐cause mortality by 12 to 24%. [30] Side effects of vitamin A supplements are rare. Vitamin A toxicity is a rare concern associated with high levels of vitamin A over prolonged periods of time.
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The pigment, called rhodopsin (conopsin is found in cone cells) comprises a large protein called opsin (situated in the plasma membrane), attached to which is a covalently bound prosthetic group: an organic molecule called retinal (a derivative of vitamin A). The retinal exists in the 11-cis-retinal form when in the dark, and stimulation by ...
Retinol, also called vitamin A 1, is a fat-soluble vitamin in the vitamin A family that is found in food and used as a dietary supplement. [3] Retinol or other forms of vitamin A are needed for vision, cellular development, maintenance of skin and mucous membranes , immune function and reproductive development. [ 3 ]
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