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Diabetic dermadromes constitute a group of cutaneous conditions commonly seen in people with diabetes with longstanding disease. [1] Conditions included in this group are: [1] [2] Acral dry gangrene; Carotenosis; Diabetic dermopathy; Diabetic bulla; Diabetic cheiroarthropathy; Malum perforans; Necrobiosis lipoidica
After the gangrene is treated with debridement and antibiotics, the underlying cause can be treated. In the case of gangrene due to critical limb ischemia, revascularization can be performed to treat the underlying peripheral underlateral artery disease. [citation needed] Ischemic disease of the legs is the most common reason for amputations.
However, diabetes does cause higher morbidity, mortality and operative risks with these conditions. [41] Diabetic foot, often due to a combination of sensory neuropathy (numbness or insensitivity) and vascular damage, increases rates of skin ulcers (diabetic foot ulcers) and infection and, in serious cases, necrosis and gangrene. It is why it ...
Diabetic foot ulcer is a breakdown of the skin and sometimes deeper tissues of the foot that leads to sore formation. It is thought to occur due to abnormal pressure or mechanical stress chronically applied to the foot, usually with concomitant predisposing conditions such as peripheral sensory neuropathy, peripheral motor neuropathy, autonomic neuropathy or peripheral arterial disease. [1]
Fournier gangrene is usually diagnosed clinically, but laboratory tests and imaging studies are used to confirm diagnosis, determine severity, and predict outcomes. [2] X-rays and ultrasounds may show the presence of gas below the surface of the skin. [2] A CT scan can be useful in determining the site of origin and extent of spread. [2]
It is characterized by dull-red papules that progress to well-circumscribed, small, round, atrophic hyperpigmented skin lesions usually on the shins. It is the most common [1]: 540 [2]: 681 of several diabetic skin conditions, being found in up to 30% of diabetics. Similar lesions can occasionally be found in non-diabetics usually following ...
In diabetes, this atherosclerosis is preferentially distributed to the posterior and anterior tibial arteries, decreasing perfusion to the lower extremities. [7] This may lead to loss of skin integrity, ischemic ulcers, and gangrene. Infection may vary in the depth of tissue to which it extends.
Diabetic angiopathy is a form of angiopathy associated with diabetic complications. [1] While not exclusive, the two most common forms are diabetic retinopathy and diabetic nephropathy, whose pathophysiologies are largely identical. Other forms of diabetic angiopathy include diabetic neuropathy and diabetic cardiomyopathy. [2] [3]