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Of those women who experience hypothyroidism associated with postpartum thyroiditis, one in five will develop permanent hypothyroidism requiring lifelong treatment. Postpartum thyroiditis is believed to result from the modifications to the immune system necessary in pregnancy, and histologically is a subacute lymphocytic thyroiditis .
One study showed infants born to treated hypothyroid mothers had abnormal thyroid function compared to matched controls. [2] Therefore, it is advised to monitor T4 levels throughout the pregnancy in case treatment dosages should be increased to accommodate both the mother’s and fetus’s thyroid hormone requirements.
Hypothyroidism is common in pregnancy with an estimated prevalence of 2-3% and 0.3-0.5% for subclinical and overt hypothyroidism respectively. [8] Endemic iodine deficiency accounts for most hypothyroidism in pregnant women worldwide while chronic autoimmune thyroiditis is the most common cause of hypothyroidism in iodine sufficient parts of the world.
He is co-Chairman of the 2017 American Thyroid Association national clinical guidelines on the treatment of Thyroid Disease during Pregnancy. [7] His work investigating thyroid physiology during pregnancy has helped to define treatment paradigms designed to prevent maternal hypothyroidism and its consequences. [8]
Hypothyroidism (also called underactive thyroid, low thyroid or hypothyreosis) is a disorder of the endocrine system in which the thyroid gland does not produce enough thyroid hormones. [3] It can cause a number of symptoms, such as poor ability to tolerate cold , extreme fatigue, muscle aches , constipation , slow heart rate , depression , and ...
Symptoms of normal pregnancy, like fatigue, can make it easy to overlook thyroid problems in pregnancy. [1] Thyroid hormone is vital during pregnancy. The unborn baby's brain and nervous system need thyroid hormone to develop. During the first trimester, the baby depends on the mother's supply of thyroid hormone. At 10 to 12 weeks of pregnancy ...
The American Thyroid Association (ATA) is a professional organization of over 1700 medical specialists devoted to thyroid biology and to the prevention and treatment of thyroid disease through excellence in research, clinical care, education, and public health. The ATA publishes the journals Clinical Thyroidology for the Public and Signal.
Thyroid disease in pregnancy can, if uncorrected, cause adverse effects on fetal and maternal well-being. The deleterious effects of thyroid dysfunction can also extend beyond pregnancy and delivery to affect neurointellectual development in the early life of the child.