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Studies examining this effect have used high ratios of CBD to THC, and it is unclear to what extent these laboratory studies translate to the types of cannabis used by real life users. [28] [40] Research has suggested that CBD can safely reduce some symptoms of psychosis in general. [41]
Acute effects while under the influence can sometimes include euphoria or anxiety. [4] [5] Although some assert that cannabidiol (CBD), another cannabinoid found in cannabis in varying amounts, may alleviate the adverse effects of THC that some users experience, [6] little is known about CBD's effects on humans.
"rare and mild gastrointestinal upset, headaches, diarrhea, gynecomastia, paroxysmal atrial fibrillation, ventricular rupture and death in one patient" [3] Senna: Egyptian senna Senna alexandrina (Cassia senna) "abdominal pain, diarrhea, potentially carcinogenic, with others can potentiate cardiac glycosides and antiarrhythmic agents", [3 ...
Abnormal cannabidiol (Abn-CBD) is a synthetic regioisomer of cannabidiol, which unlike most other cannabinoids produces vasodilator effects, lowers blood pressure, and induces cell migration, cell proliferation and mitogen-activated protein kinase activation in microglia, but without producing any psychoactive or sedative effects.
Weekly cannabis use is generally required for the syndrome to occur; synthetic cannabinoids can also cause CHS. [6] [5] The underlying mechanism is unclear, with several possibilities proposed. [2] [5] Diagnosis is based on the symptoms, as well as the history of cannabis use (including a urine screen test if necessary). [6]
The cough started when I was around 25 or 26. I noticed it right before the pandemic, and I didn’t have a bad flu or anything that brought it on. It was consistent, and I had to clear my throat ...
[4] [20] CBD does not have the same psychoactivity as THC, [25] [26] and can modulate the psychoactive effects of THC on the body if both are present. [17] [25] [27] [28] Conversion of CBD to THC can occur when CBD is heated to temperatures between 250–300 °C, potentially leading to its partial transformation into THC. [29]
People sometimes use cannabis to cope with their anxiety, and cannabis withdrawal can lead to symptoms of anxiety. [58] Buspirone , a serotonin 5-HT 1A receptor partial agonist , has shown limited efficacy for treating anxiety in people with cannabis use disorder, though there may be better efficacy in males than in females. [ 58 ]