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The first two steps are performed individually on each sample and the last step looks at the overlap in all samples. However, the analysis can be run on one sample as well. SplicePlot is a tool for visualizing alternative splicing and the effects of splicing quantitative trait loci (sQTLs) from RNA-seq data. It provides a simple command line ...
Diffusion maps exploit the relationship between heat diffusion and random walk Markov chain.The basic observation is that if we take a random walk on the data, walking to a nearby data-point is more likely than walking to another that is far away.
The sample covariance matrix (SCM) is an unbiased and efficient estimator of the covariance matrix if the space of covariance matrices is viewed as an extrinsic convex cone in R p×p; however, measured using the intrinsic geometry of positive-definite matrices, the SCM is a biased and inefficient estimator. [1]
The Wishart distribution arises as the distribution of the sample covariance matrix for a sample from a multivariate normal distribution. It occurs frequently in likelihood-ratio tests in multivariate statistical analysis. It also arises in the spectral theory of random matrices [citation needed] and in multidimensional Bayesian analysis. [5]
Whitening a data matrix follows the same transformation as for random variables. An empirical whitening transform is obtained by estimating the covariance (e.g. by maximum likelihood) and subsequently constructing a corresponding estimated whitening matrix (e.g. by Cholesky decomposition).
In the simplest cases, normalization of ratings means adjusting values measured on different scales to a notionally common scale, often prior to averaging. In more complicated cases, normalization may refer to more sophisticated adjustments where the intention is to bring the entire probability distributions of adjusted values into alignment.
The probability density function for the random matrix X (n × p) that follows the matrix normal distribution , (,,) has the form: (,,) = ([() ()]) / | | / | | /where denotes trace and M is n × p, U is n × n and V is p × p, and the density is understood as the probability density function with respect to the standard Lebesgue measure in , i.e.: the measure corresponding to integration ...
One-sided normal tolerance intervals have an exact solution in terms of the sample mean and sample variance based on the noncentral t-distribution. [8] This enables the calculation of a statistical interval within which, with some confidence level, a specified proportion of a sampled population falls.