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Aminoglycosides are useful primarily in infections involving aerobic, Gram-negative bacteria, such as Pseudomonas, Acinetobacter, and Enterobacter. In addition, some Mycobacteria, including the bacteria that cause tuberculosis, are susceptible to aminoglycosides. Streptomycin was the first effective drug in the treatment of tuberculosis, though ...
Gentamicin is an aminoglycoside antibiotic used to treat several types of bacterial infections. [5] This may include bone infections, endocarditis, pelvic inflammatory disease, meningitis, pneumonia, urinary tract infections, and sepsis among others. [5] It is not effective for gonorrhea or chlamydia infections. [5]
While amikacin is only FDA-approved for use in dogs and for intrauterine infection in horses, it is one of the most common aminoglycosides used in veterinary medicine, [35] and has been used in dogs, cats, guinea pigs, chinchillas, hamsters, rats, mice, prairie dogs, cattle, birds, snakes, turtles and tortoises, crocodilians, bullfrogs, and fish.
However, these classifications are based on laboratory behavior. The development of antibiotics has had a profound effect on the health of people for many years. Also, both people and animals have used antibiotics to treat infections and diseases. In practice, both treat bacterial infections. [1]
Tobramycin is an aminoglycoside antibiotic derived from Streptomyces tenebrarius that is used to treat various types of bacterial infections, particularly Gram-negative infections. It is especially effective against species of Pseudomonas. [9] It was patented in 1965, and approved for medical use in 1974. [10]
Kanamycin A, [2] often referred to simply as kanamycin, is an antibiotic used to treat severe bacterial infections and tuberculosis. [3] It is not a first line treatment. [3] It is used by mouth, injection into a vein, or injection into a muscle. [3] Kanamycin is recommended for short-term use only, usually from 7 to 10 days. [3]
Plazomicin, sold under the brand name Zemdri, is an aminoglycoside antibiotic used to treat complicated urinary tract infections. [2] As of 2019 it is recommended only for those in whom alternatives are not an option. [2] It is given by injection into a vein. [2] Common side effects include kidney problems, diarrhea, nausea, and blood pressure ...
Sisomicin is inactivated by the same enzymes as gentamicin, but it is active against many organisms that resist gentamicin by non-enzymatic mechanisms. [ 4 ] Some studies show that sisomicin has been effective in the treatment of infections that either had failed to respond to other drugs or were due to microorganisms resistant in vitro to ...
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