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  2. Timeline of antibiotics - Wikipedia

    en.wikipedia.org/wiki/Timeline_of_antibiotics

    1942 – gramicidin S, the first peptide antibiotic; 1942 – sulfadimidine; 1943 – sulfamerazine; 1944 – streptomycin, the first aminoglycoside [2] 1947 – sulfadiazine; 1948 – chlortetracycline, the first tetracycline; 1949 – chloramphenicol, the first amphenicol [2] 1949 – neomycin; 1950 – oxytetracycline; 1950 – penicillin G ...

  3. List of drugs by year of discovery - Wikipedia

    en.wikipedia.org/wiki/List_of_drugs_by_year_of...

    In 1907 Alfred Bertheim synthesized Arsphenamine, the first man-made antibiotic. In 1927 Erik Rotheim patented the first aerosol spray can. In 1933 Robert Pauli Scherer created a method to develop softgels. William Roberts studies about penicillin were continued by Alexander Fleming, who in 1928 concluded that penicillin had an antibiotic ...

  4. History of pharmacy - Wikipedia

    en.wikipedia.org/wiki/History_of_pharmacy

    [1] [2] For example, herbs were discovered in the Shanidar Cave, and remains of the areca nut (Areca catechu) in the Spirit Cave. [3]: 8 Prehistoric man learned pharmaceutical techniques through instinct, by watching birds and beasts, and using cool water, leaves, dirt, or mud as a soothing agent. [4]

  5. History of penicillin - Wikipedia

    en.wikipedia.org/wiki/History_of_penicillin

    The article was translated into Japanese, and production of penicillin was underway by 1 February 1944. By mid-May, a research team under Hamao Umezawa had tested 750 different strains of mould and found that 75 exhibited antibiotic activity. Experiments were conducted on mice to determine efficacy and toxicity.

  6. Timeline of medicine and medical technology - Wikipedia

    en.wikipedia.org/wiki/Timeline_of_medicine_and...

    500 BC – Pills were used. They were presumably invented so that measured amounts of a medicinal substance could be delivered to a patient. 510–430 BC – Alcmaeon of Croton scientific anatomic dissections. He studied the optic nerves and the brain, arguing that the brain was the seat of the senses and intelligence.

  7. Ernest Duchesne - Wikipedia

    en.wikipedia.org/wiki/Ernest_Duchesne

    Ernest Duchesne (30 May 1874 – 12 April 1912) was a French physician who noted that certain molds kill bacteria.He made this discovery 32 years before Alexander Fleming discovered the antibiotic properties of penicillin, a substance derived from those molds, but his research went unnoticed.

  8. Drug discovery - Wikipedia

    en.wikipedia.org/wiki/Drug_discovery

    A 2007 report [56] found that of the 974 small molecule new chemical entities developed between 1981 and 2006, 63% were natural derived or semisynthetic derivatives of natural products. For certain therapy areas, such as antimicrobials, antineoplastics, antihypertensive and anti-inflammatory drugs, the numbers were higher. [citation needed]

  9. Discovery of penicillin - Wikipedia

    en.wikipedia.org/wiki/Discovery_of_penicillin

    Many ancient cultures, including those in Australia, China, Egypt, Greece and India, independently discovered the useful properties of fungi and plants in treating infection. These treatments often worked because many organisms, including many species of mould, naturally produce antibiotic substances. However, ancient practitioners could not ...