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Aspirin-exacerbated respiratory disease (AERD), also called NSAID-exacerbated respiratory disease (N-ERD) or historically aspirin-induced asthma and Samter's Triad, is a long-term disease defined by three simultaneous symptoms: asthma, chronic rhinosinusitis with nasal polyps, and intolerance of aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs).
A combination of topical and systematic antibiotics taken prophylactically can prevent infection and improve adults' overall mortality in the ICU for adult patients receiving mechanical ventilation for at least 48 hours, and topical antibiotic prophylaxis probably reduces respiratory infections but not mortality. [24]
An acute exacerbation of COPD is associated with increased frequency and severity of coughing. [5] It is often accompanied by worsened chest congestion and discomfort. Shortness of breath and wheezing are present in many cases. [5] Exacerbations may be accompanied by increased amount of cough and sputum productions, and a change in appearance ...
Nasal obstruction characterized by insufficient airflow through the nose can be a subjective sensation or the result of objective pathology. [10] It is difficult to quantify by subjective complaints or clinical examinations alone, hence both clinicians and researchers depend both on concurrent subjective assessment and on objective measurement of the nasal airway.
Acute exacerbation of underlying chronic illness (COPD, asthma, congestive heart failure) [4] Permanent decline in lung function in patients with COPD [3] Immunocompromised Some immunocompromised groups are at higher risk of specific complications, such as: Bone marrow transplant recipients → pneumonia, death [3]
The FDA's nasal decongestants drug list, or monograph, has not been updated since 1995. The process for changing a monograph has traditionally taken years or decades, requiring multiple rounds of ...
Asthma being a reversible obstruction of airways is often considered separately, but many COPD patients also have some degree of reversibility in their airways. [ 7 ] In COPD, there is an increase in airway resistance , shown by a decrease in the forced expiratory volume in 1 second (FEV1) measured by spirometry .
Sinus congestion from allergies or an infection may cause pain that is localized around the front of the head in the sinuses, according to Healthline. The pain typically goes away after the sinus ...
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