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A clue to the cause of intoxication is the presence of oxalate crystals in the urine. Like methanol intoxication, treatment is ethanol consumption. Ethambutol, a drug commonly used to treat tuberculosis, is notorious for causing toxic optic neuropathy. People with vision loss from ethambutol toxicity lose vision in both eyes equally.
Symptoms of endophthalmitis include severe eye pain, vision loss, and intense redness of the conjunctiva. [1] Bacterial endophthalmitis more commonly presents with severe and sudden symptoms whereas fungal causes have a more insidious onset and severity, with 80% of ocular candidiasis (both chorioretinitis and endophthalmitis) being asymptomatic. [3]
Angle-closure glaucoma should be considered if there is painful loss of vision with a red eye, nausea or vomiting. [4] The eye pressure will be very high typically greater than 40 mmHg. [5] Emergent laser treatment to the iris may prevent blindness. [4]
Vision loss in toxic and nutritional optic neuropathy is bilateral, symmetric, painless, gradual, and progressive. Dyschromatopsia, a change in color vision, is often the first symptom. Some patients notice that certain colors, particularly red, are less bright or vivid; others have a general loss of color perception.
Major symptoms are sudden loss of vision (partial or complete), sudden blurred or "foggy" vision, and; pain on movement of the affected eye. [4] [5] [2]Many patients with optic neuritis may lose some of their color vision in the affected eye (especially red), with colors appearing subtly washed out compared to the other eye.
[2] [5] At onset vision loss is unilateral, but without treatment it rapidly progresses to involve both eyes. Vision loss is usually severe, ranging from counting fingers to no light perception. Associated symptoms are jaw pain exacerbated by chewing, scalp tenderness, shoulder and hip pain, headache and fatigue. [3] [4]
Photokeratitis or ultraviolet keratitis is a painful eye condition caused by exposure of insufficiently protected eyes to the ultraviolet (UV) rays from either natural (e.g. intense direct or reflected sunlight) or artificial (e.g. the electric arc during welding) sources.
NAION is the most common cause of sudden optic nerve-related vision loss, affecting more than 10,000 Americans every year, often bilaterally. No clinically effective treatments exist, largely because little is known about its pathophysiology, and there are few histopathological studies of the acute condition. [12]
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