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A cell during anaphase. Microtubules are visible in green. Stages of late M phase in a vertebrate cell. Anaphase (from Ancient Greek ἀνα-() 'back, backward' and φάσις (phásis) 'appearance') is the stage of mitosis after the process of metaphase, when replicated chromosomes are split and the newly-copied chromosomes (daughter chromatids) are moved to opposite poles of the cell.
Chromosome segregation occurs at two separate stages during meiosis called anaphase I and anaphase II (see meiosis diagram). In a diploid cell there are two sets of homologous chromosomes of different parental origin (e.g. a paternal and a maternal set).
The cell cycle in eukaryotes: I = Interphase, M = Mitosis, G 0 = Gap 0, G 1 = Gap 1, G 2 = Gap 2, S = Synthesis, G 3 = Gap 3. Cell division is the process by which a parent cell divides into two daughter cells. [1] Cell division usually occurs as part of a larger cell cycle in which the cell grows and replicates its chromosome(s) before dividing.
This is an accepted version of this page This is the latest accepted revision, reviewed on 19 December 2024. Cell division producing haploid gametes For the figure of speech, see Meiosis (figure of speech). For the process whereby cell nuclei divide to produce two copies of themselves, see Mitosis. For excessive constriction of the pupils, see Miosis. For the parasitic infestation, see Myiasis ...
The eukaryotic cell cycle consists of four distinct phases: G 1 phase, S phase (synthesis), G 2 phase (collectively known as interphase) and M phase (mitosis and cytokinesis). M phase is itself composed of two tightly coupled processes: mitosis, in which the cell's nucleus divides, and cytokinesis, in which the cell's cytoplasm and cell membrane divides forming two daughter cells.
In the anaphase of mitosis, sister chromatids separate and migrate to opposite cell poles before the cell divides. Nondisjunction during mitosis leads to one daughter receiving both sister chromatids of the affected chromosome while the other gets none. [2] [3] This is known as a chromatin bridge or an anaphase bridge.
After checkpoint deactivation and during the normal anaphase of the cell cycle, the anaphase promoting complex is activated through decreasing MCC activity. When this happens the enzyme complex polyubiquitinates the anaphase inhibitor securin. The ubiquitination and destruction of securin at the end of metaphase releases the active protease ...
9700 105988 Ensembl ENSG00000135476 ENSMUSG00000058290 UniProt Q14674 P60330 RefSeq (mRNA) NM_012291 NM_001014976 NM_001356312 RefSeq (protein) NP_036423 NP_001014976 NP_001343241 Location (UCSC) Chr 12: 53.27 – 53.29 Mb Chr 15: 102.2 – 102.23 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Separase, also known as separin, is a cysteine protease responsible for triggering ...