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12156 Ensembl ENSG00000125845 ENSMUSG00000027358 UniProt P12643 P21274 RefSeq (mRNA) NM_001200 NM_007553 RefSeq (protein) NP_001191 NP_031579 Location (UCSC) Chr 20: 6.77 – 6.78 Mb Chr 2: 133.39 – 133.4 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Bone morphogenetic protein 2 or BMP-2 belongs to the TGF-β superfamily of proteins. Function BMP-2 like other bone morphogenetic ...
Bone morphogenetic proteins (BMPs) are a group of growth factors also known as cytokines and as metabologens. [1] Professor Marshall Urist and Professor Hari Reddi discovered their ability to induce the formation of bone and cartilage, BMPs are now considered to constitute a group of pivotal morphogenetic signals, orchestrating tissue architecture throughout the body.
Type 1 contains a glycine-serine-rich domain to be phosphorylated by type 2 kinase domain, initiating the signaling transduction pathway of the SMAD signaling cascade. [3] The wrist epitope motif on BMP-2 has a high-affinity binding site for BMPR-IA. The knuckle epitope motif on BMP-2 has a low-affinity binding site for BMPR-II. [4]
After earning his M.D. degree in 2002, [6] Smoljanović worked as a physician at the Department of Orthopaedics of the University Hospital Centre in Zagreb. [7] In 2006, while examining the available literature on bone morphogenetic protein 2 (BMP-2), used to stimulate bone growth in spinal fusion procedures, Smoljanović and his colleagues discovered that BMP-2 therapy had major side effects ...
12168 Ensembl ENSG00000204217 ENSMUSG00000067336 UniProt Q13873 O35607 RefSeq (mRNA) NM_001204 NM_033346 NM_007561 RefSeq (protein) NP_001195 NP_031587 Location (UCSC) Chr 2: 202.38 – 202.57 Mb Chr 1: 59.8 – 59.92 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Bone morphogenetic protein receptor type II or BMPR2 is a serine/threonine receptor kinase encoded by the BMPR2 gene. It ...
The DRDO Armoured Ambulance is a tracked military ambulance based on "Sarath" ("Chariot of Victory") Indian license-produced variant of BMP-2. Designed by the Combat Vehicles Research and Development Establishment (CVRDE), a branch of the Defence Research and Development Organisation , it is manufactured at the AVANI.
BMP2 or BMP-2 may refer to: Bone morphogenetic protein 2; Boyevaya Mashina Pekhoty , a Soviet infantry fighting vehicle; See also. BMP (disambiguation)
Bone morphogenetic protein 5 is a protein that in humans is encoded by the BMP5 gene. [5] [6] [7] The protein encoded by this gene is member of the TGFβ superfamily. Bone morphogenetic proteins are known for their ability to induce bone and cartilage development. BMP5 may play a role in certain cancers. Like other BMP's BMP5 is inhibited by ...