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On July 22, 2020, the U.S. government placed a conditional advance-purchase order of $2 billion with Pfizer to manufacture 100 million doses of a COVID-19 vaccine, with an option for 500 million more, for use in the United States if the vaccine was shown to be safe, effective, licensed, and authorized by the Food and Drug Administration (FDA).
A test-negative [note 1] case-control study published in August 2021, found that two doses of the BNT162b2 (Pfizer) vaccine had 93.7% effectiveness against symptomatic disease caused by the alpha (B.1.1.7) variant and 88.0% effectiveness against symptomatic disease caused by the delta (B.1.617.2) variant. [87]
It suggests that personalization of the vaccine dose (regular dose to the elderly, reduced dose to the healthy young, [359] additional booster dose to the immunosuppressed [360]) might allow accelerating vaccination campaigns in settings of limited supplies, thereby shortening the pandemic, as predicted by pandemic modeling.
How COVID‑19 vaccines work. The video shows the process of vaccination, from injection with RNA or viral vector vaccines, to uptake and translation, and on to immune system stimulation and effect. Part of a series on the COVID-19 pandemic Scientifically accurate atomic model of the external structure of SARS-CoV-2. Each "ball" is an atom. COVID-19 (disease) SARS-CoV-2 (virus) Cases Deaths ...
At this point the object stops accelerating and continues falling at a constant speed called the terminal velocity (also called settling velocity). An object moving downward faster than the terminal velocity (for example because it was thrown downwards, it fell from a thinner part of the atmosphere, or it changed shape) will slow down until it ...
LONDON (Reuters) -The European Commission has secured deals with Pfizer and several European drugmakers to reserve capacity to make up to 325 million vaccines per year in case of a future global ...
For example, the Pfizer-BioNTech COVID‑19 vaccine must be shipped and stored between −80 and −60 °C (−112 and −76 °F), [165] must be used within five days of thawing, [165] and has a minimum order of 975 doses, making it unlikely to be rolled out in settings other than large, well-equipped hospitals. [166]
[15] [16] On 2 December 2020, the United Kingdom's Medicines and Healthcare products Regulatory Agency (MHRA) gave temporary regulatory approval for the Pfizer–BioNTech vaccine, [17] [18] becoming the first country to approve this vaccine and the first country in the Western world to approve the use of any COVID‑19 vaccine.