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5' AMP-activated protein kinase or AMPK or 5' adenosine monophosphate-activated protein kinase is an enzyme (EC 2.7.11.31) that plays a role in cellular energy homeostasis, largely to activate glucose and fatty acid uptake and oxidation when cellular energy is low.
AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming ...
AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase ( HMGCR ), key enzymes involved in regulating de novo biosynthesis of fatty acid ...
(Reuters) -U.S. President-elect Donald Trump said in an interview aired on Sunday he will not try to replace Federal Reserve Chair Jerome Powell upon taking office in January. Trump added that he ...
WASHINGTON (Reuters) -President-elect Donald Trump said on Saturday the U.S. should not be involved in the conflict in Syria, where rebel forces are threatening the government of President Bashar ...
On Dec. 6, the family received a phone call from immigration authorities and they were told to report to an office in Greenspoint, Texas, four days later to discuss Salazar-Hinojosa's case ...
PRKAB1 has been shown to interact with PRKAG2 [7] and PRKAG1. [7]The 5'-AMP-activated protein kinase beta subunit interaction domain (AMPKBI) is a conserved domain found in the beta subunit of the 5-AMP-activated protein kinase complex, and its yeast homologues Sip1 (SNF1-interacting protein 1), Sip2 (SNF1-interacting protein 2) and Gal83 (galactose metabolism 83), which are found in the SNF1 ...
AMPK may refer to: AMP-activated protein kinase, an enzyme (acetyl-CoA carboxylase) kinase, an enzyme This page was last edited on 15 May 2022, at ...