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This exceedingly high uniformity means that fewer individuals are required to produce results with the same level of statistical significance when an inbred line is used in comparison to an outbred line in the same experiment. [6] Breeding of inbred strains is often towards specific phenotypes of interest such as behavioural traits like alcohol ...
Inbreeding is the production of offspring from the mating or breeding of individuals or organisms that are closely related genetically. [1] By analogy, the term is used in human reproduction , but more commonly refers to the genetic disorders and other consequences that may arise from expression of deleterious recessive traits resulting from ...
The origins and history of recombinant inbred strains are described by Crow. [1] While the potential utility of recombinant inbred strains in mapping analysis of complex polygenic traits was obvious from the outset, the small number of strains only made it feasible to map quantitative traits with very large effects (quasi-Mendelian loci).
Line breeding is differentiated from inbreeding by excluding pairings between parents and offspring, and between full siblings. Outcrossing is the planned breeding between two unrelated dogs, used to increase genetic diversity in a breed and decrease genetic issues or abnormalities inherited from line breeding or inbreeding.
Breeding from too small a gene pool, especially direct inbreeding, can lead to the passing on of undesirable characteristics or even a collapse of a breed population due to inbreeding depression. Therefore, there is a question, and often heated controversy, as to when or if a breed may need to allow "outside" stock in for the purpose of ...
In plants, the term inbred backcross line (IBL) refers to a line (i.e. population) of plants derived from the repeated backcrossing of a line with artificially recombinant DNA with the wild type, operating some kind of selection that can be phenotypical or through a molecular marker (for the production of an introgression line).
Many thoroughbred breeding theories are implemented from other animal breeding stock practices, such as the use of inbreeding to "fix a type". Some breeding theories are qualitative, relying on judgement. Quantitative breeding theories usually focus on statistical analysis of the sire and broodmare sires in particular.
The detection of the usefulness of heterosis for plant breeding has led to the development of inbred lines that reveal a heterotic yield advantage when they are crossed. Maize was the first species where heterosis was widely used to produce hybrids.