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The underlying reason for its occurrence is unclear. [2] The diagnosis is based on the symptoms. [2] Methods of prevention include gradually decreasing the dose among those who wish to stop, though it is possible for symptoms to occur with tapering. [2] [6] [4] Treatment may include restarting the medication and slowly decreasing the dose. [2]
Mirtazapine, sold under the brand name Remeron among others, is an atypical tetracyclic antidepressant, and as such is used primarily to treat depression. [11] [12] Its effects may take up to four weeks but can also manifest as early as one to two weeks. [12] [13] It is often used in cases of depression complicated by anxiety or insomnia.
Although usually reversible, these sexual side-effects can, in rare cases, continue after the drug has been completely withdrawn. [158] [159] In a study of 1,022 outpatients, overall sexual dysfunction with all antidepressants averaged 59.1% [160] with SSRI values between 57% and 73%, mirtazapine 24%, nefazodone 8%, amineptine 7%, and ...
Serotonin reuptake inhibitors should not be abruptly discontinued after extended therapy, and whenever possible, should be tapered over several weeks to minimize discontinuation-related symptoms which may include nausea, headache, dizziness, chills, body aches, paresthesias, insomnia, and brain zaps. Paroxetine may produce discontinuation ...
The consensus is to reduce dosage gradually over several weeks, e.g. 4 or more weeks for diazepam doses over 30 mg/day, [1] with the rate determined by the person's ability to tolerate symptoms. [120] The recommended reduction rates range from 50% of the initial dose every week or so, [121] to 10–25% of the daily dose every 2 weeks. [120]
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Meanwhile, those who continued the treatment experienced an additional 5.5% weight reduction during the 52-week period, data from the study showed. Shares of Eli Lilly fell over 4% in morning trading.
The treatment benefits of antidepressant medications are often not seen until 1–2 weeks into treatment, with maximum benefits reached around 4–6 weeks. Likely, the person will experience more negative side effects during the first week or two and may want to stop taking the medication.