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Diabetes mellitus: its differentiation into insulin-sensitive and insulin-insensitive types. Author: Himsworth HP Publication data: Lancet 1936;i:127-130. Online version: Description: Himsworth noted that there are two main types of diabetes, the insulin-depleted (type 1) and the insulin-resistant form (type 2).
Diabetes also publishes abstracts presented at the ADA's annual meeting, Scientific Sessions, as a supplement. According to the Journal Citation Reports , the journal has a 2021 impact factor of 9.337, and a 5 years impact factor of 10.509 ranking it 8th out of 240 journals in the category "Endocrinology, Diabetes & Metabolism".
The PPARGC1A gene regulates genes involved in energy metabolism. [1] [2] Since type 2 diabetes is characterized by chronic hyperglycaemia as a result of impaired pancreatic beta cell function [3] and insulin resistance in peripheral tissues, [4] it was thought that the gene might be downregulated in type 2 diabetes patients through DNA methylation.
This is an accepted version of this page This is the latest accepted revision, reviewed on 1 March 2025. Group of endocrine diseases characterized by high blood sugar levels This article is about the common insulin disorder. For the urine hyper-production disorder, see Diabetes insipidus. For other uses, see Diabetes (disambiguation). Medical condition Diabetes Universal blue circle symbol for ...
Today, the term "diabetes" most commonly refers to diabetes mellitus. Diabetes mellitus is itself an umbrella term for a number of different diseases involving problems processing sugars that have been consumed (glucose metabolism). Historically, this is the "diabetes" which has been associated with sugary urine .
Due to the prevalence of diabetes, it is the prime drive in the construction of fluorescent biosensors. A recent development has been approved by the FDA allowing a new continuous glucose monitoring system called EverSense, which is a 90-day glucose monitor using fluorescent biosensors.
Public messages from the United States Surgeon General, World Health Organization, and World Cancer Research Fund have resulted from the findings of the Nurses' Health Study. [40] Policies such as the 2008 Physical Activity Guidelines for Americans and the Dietary Guidelines of the Food and Drug Administration regarding trans-fat related to the ...
Their work together resulted in the discovery of the 2 forms of diabetes – insulin dependent diabetes mellitus (IDDM) and non-insulin dependent diabetes mellitus (NIDDM). [25] This discovery in 1949 “..literally changed the concepts, research and treatment of diabetes". [26]: 37