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Ly6 proteins are characterized by the LU domain.Typically, they contain one LU domain, but some members of the family have multiple LU domains.The LU domain consists of 60-80 AA and contains 10 cysteines arranged in a specific pattern that allows the creation of 5 disulfide bridges which in turn allow the formation of a three-fingered (3F) structural motif.
Proliferation, as one of the hallmarks and most fundamental biological processes in tumors, [1] is associated with tumor progression, response to therapy, and cancer patient survival. [2] Consequently, the evaluation of a tumor proliferative index (or growth fraction) has clinical significance in characterizing many solid tumors and hematologic ...
Lymphocyte antigen 6E is a protein that in humans is encoded by the LY6E gene. [5] [6] [7] Increased expression of Ly6E is associated with poor survival outcome in multiple malignancies as determined by a survey of more than 130 published clinical studies of gene expression studies on cancer tissue samples and adjacent normal tissues. [8]
Gene expression profiling is a technique used in molecular biology to query the expression of thousands of genes simultaneously. In the context of cancer, gene expression profiling has been used to more accurately classify tumors. The information derived from gene expression profiling often helps in predicting the patient's clinical outcome.
Tumor markers can be molecules that are produced in higher amounts by cancer cells than normal cells, but can also be produced by other cells from a reaction with the cancer. [ 2 ] The markers can't be used to give patients a diagnosis but can be compared with the result of other tests like biopsy or imaging.
U.S. stocks ripped higher and carried the S&P 500 to records as the economy kept growing and the Federal Reserve began cutting interest rates. The year featured many familiar winners, such as Big ...
The Cancer Genome Atlas →: National Cancer Institute, United States Copy number, Mutation, Methylation, Gene Expression, miRNA expression: Yes Yes Human: No Yes Yes CancerResource →: University Medicine Berlin, Germany Roche Cancer Genome Database (RCGDB) Roche Diagnostics, Penzberg, Germany Network of Cancer Genes →: King's College ...
By Gwladys Fouche and Tom Little. OSLO (Reuters) -A tram derailed and crashed into a store in central Oslo on Tuesday, injuring the driver and at least three other people, Norwegian police said.