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Danicopan, sold under the brand name Voydeya, is a medication used for the treatment of paroxysmal nocturnal hemoglobinuria. It is a complement inhibitor which reversibly binds to factor D to prevent alternative pathway-mediated hemolysis and deposition of complement C3 proteins on red blood cells. The most common side effects include fever, headache, increased levels of liver enzymes (a sign ...
Bleeding may be either external or internal. [3] A substantial amount of blood loss to the point of hemodynamic compromise may occur in the chest, abdomen, or the retroperitoneum. [3] The thigh itself can hold up to 1 L to 2 L of blood. [3] Localizing and controlling the source of bleeding is of utmost importance to the treatment of hemorrhagic ...
Signs of external bleeding should be assessed, noting that individuals can bleed internally without external blood loss or otherwise apparent signs. [ 16 ] There should be considered possible mechanisms of injury that may have caused internal bleeding, such as ruptured or bruised internal organs.
Cold-induced diuresis, or cold diuresis, is a phenomenon that occurs in humans after exposure to a hypothermic environment, usually during mild to moderate hypothermia. [16] It is currently thought to be caused by the redirection of blood from the extremities to the core due to peripheral vasoconstriction , which increases the fluid volume in ...
Two new studies indicate the importance of getting a good night's sleep — with one study saying a lack of sleep may be sabotaging the brain’s ability to keep intrusive thoughts at bay.
A functional disorder of the spleen or kidneys would lead to qi stagnation and blood stasis. Some causes of blood stasis are believed to include: too little nutrients, too much sugar, too little sleep, too much alcohol, lack of movement, too much movement (over-training), emotional stress, trauma, heat in the body, and cold in the body. [3]
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Yalda Night, or Shab-e Yalda (also spelled Shabe Yalda), marks the longest night of the year in Iran and in many other Central Asian and Middle Eastern countries. On the winter solstice, in a ...