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Herpes simplex virus 1 (cold sores) and 2 (genital herpes) (HSV-1 and HSV-2), also known by their taxonomic names Human alphaherpesvirus 1 and Human alphaherpesvirus 2, are two members of the human Herpesviridae family, a set of viruses that produce viral infections in the majority of humans. [1] [2] Both HSV-1 and HSV-2 are very common and ...
Due to the genetic similarity of both herpes simplex virus types (HSV-1 and HSV-2), the development of a prophylactic-therapeutic vaccine that proves effective against one type of the virus would likely prove effective for the other virus type, or at least provide most of the necessary fundamentals.
There are two types of herpes simplex virus, type 1 (HSV-1) and type 2 (HSV-2). [1] HSV-1 more commonly causes infections around the mouth while HSV-2 more commonly causes genital infections. [2] They are transmitted by direct contact with body fluids or lesions of an infected individual. [1] Transmission may still occur when symptoms are not ...
Genital herpes is a herpes infection of the genitals caused by the herpes simplex virus (HSV). [1] Most people either have no or mild symptoms and thus do not know they are infected. [ 1 ] When symptoms do occur, they typically include small blisters that break open to form painful ulcers . [ 1 ]
Human alphaherpesvirus 2 is periodically shed in the human genital tract, most often asymptomatically. Most sexual transmissions occur during periods of asymptomatic shedding. [ 5 ] Asymptomatic reactivation means that the virus causes atypical, subtle, or hard-to-notice symptoms that are not identified as an active herpes infection, so ...
HHV-2: Herpes simplex virus-2 (HSV-2) α: Mucoepithelial: Oral and/or genital herpes, herpetic gingivostomatitis, pharyngitis, eczema herpeticum, herpetic whitlow, herpes simplex keratitis, erythema multiforme, Mollaret's meningitis, as well as other herpes simplex infections: Neuron (sensory ganglia) Close contact (oral or sexually transmitted ...
Infection by the type 1 strain of herpes simplex virus (HSV-1) is most common; however, cases of oral infection by the type 2 strain are increasing. [14] Oral HSV-2 shedding is rare, and "usually noted in the context of first episode genital herpes." [21] In general, both types can cause oral or genital herpes. [22] [23] [24] Cold sores are the ...
Treatment is usually supportive in nature while also providing antiviral drug therapy. The primary exception to this is herpes simplex encephalitis, which is treatable with acyclovir . Prognosis is good for most individuals who are infected by an encephalitic virus but is poor among those who develop severe symptoms, including viral encephalitis.
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