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Obesity has been associated with an inflammatory state, which is chronic and low-grade inflammation, known as meta-inflammation. [6] [7] Meta-inflammation is subclinical meaning that while there is an increase in circulating pro-inflammatory factors, no clinical signs of inflammation, heat, pain, and redness, are seen with meta-inflammation. [8]
Death rate from obesity, 2019. Obesity is a risk factor for many chronic physical and mental illnesses.. The health effects of being overweight but not obese are controversial, with some studies showing that the mortality rate for individuals who are classified as overweight (BMI 25.0 to 29.9) may actually be lower than for those with an ideal weight (BMI 18.5 to 24.9). [1]
Central obesity is a key feature of the syndrome, as both a sign and a cause, in that the increasing adiposity often reflected in high waist circumference may both result from and contribute to insulin resistance. However, despite the importance of obesity, affected people who are of normal weight may also be insulin-resistant and have the ...
The pathophysiology of obesity involves many possible pathophysiological mechanisms involved in its development and maintenance. [25] [26] This field of research had been almost unapproached until the leptin gene was discovered in 1994 by J. M. Friedman's laboratory. [27] These investigators postulated that leptin was a satiety factor.
Clinical manifestations of hyperlipidemias (xanthelasmas, xanthomas, premature arcus cornealis) ... (5–10% of body weight loss) and reduction of abdominal obesity ...
While there is no clinical definition of the term, some experts refer to “food noise” as a heightened or persistent manifestation of ... DO, a clinical endocrinologist and obesity specialist ...
Obesity is a major cause of disability and is correlated with various diseases and conditions, particularly cardiovascular diseases, type 2 diabetes, obstructive sleep apnea, certain types of cancer, and osteoarthritis. [2] [12] [13] Obesity has individual, socioeconomic, and environmental causes.
Obesity medicine is a field of medicine dedicated to the comprehensive treatment of patients with obesity. Obesity medicine takes into account the multi-factorial etiology of obesity in which behavior, development, environment, epigenetic , genetic , nutrition , physiology , and psychosocial contributors all play a role. [ 1 ]