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The Scale for the Assessment of Negative Symptoms (SANS) is a rating scale that mental health professionals use to measure negative symptoms in schizophrenia.Negative symptoms are those conspicuous by their absence—lack of concern for one's appearance, and lack of language and communication skills, for example.
However, if properly assessed, secondary negative symptoms are amenable to treatment. [46] There is some evidence that the negative symptoms of schizophrenia are amenable to psychostimulant medication, although such drugs have varying degrees of risk for causing positive psychotic symptoms. [53]
Symptoms of schizophrenia simplex include an absence of will, impoverished thinking and flattening of affect. There is a gradual deterioration of functioning with increased amotivation and reduced socialization. [6] [7] It is considered to be rarely diagnosed and is a schizophrenia without psychotic symptoms. [8]
The name refers to the two types of symptoms in schizophrenia, as defined by the American Psychiatric Association: positive symptoms, which refer to an excess or distortion of normal functions (e.g., hallucinations and delusions), and negative symptoms, which represent a diminution or loss of normal functions. Some of these functions which may ...
Cognitive and negative symptoms: Well tolerated: 3 DB-RPCTs: 120: Agonist at α 7 nAChRs; antagonist at 5-HT 3. Expensive (>$20 AUD/tablet). Antidepressants [77] Escitalopram† [78] Negative symptoms: Well tolerated: 1 DB-RPCT: 40: May increase risk of QT interval prolongation. Fluoxetine: Negative symptoms: Well tolerated: 4 DB-RPCTs (3 ...
The prevalence of schizophrenia in adults age 65 and older ranges from 0.1 to 0.5%. [21] Aging is associated with exacerbation of schizophrenia symptoms. [22] Positive symptoms tend to lessen with age, but negative symptoms and cognitive impairments continue to worsen. [22] [23] [24]
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