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Nature Made is an American vitamin brand, founded in 1971 by Barry Pressman and Henry Burdick. [ 1 ] [ 2 ] Operating as a brand of Pharmavite , [ 3 ] Nature Made manufactures over 150 different types of supplements. [ 2 ]
Pharmavite is an American vitamin and supplement company, based in West Hills, California and founded in 1971 by Barry Pressman and Henry Burdick. Its Nature Made vitamin brand was launched that same year. [2]
Doses greater than 40 000 IU (1000 μg) per day are generally required before high blood calcium occurs. [12] Normal doses, 800–2000 IU per day, are safe in pregnancy. [5] Cholecalciferol was first described in 1936. [13] It is on the World Health Organization's List of Essential Medicines. [14]
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Once made, the product is released into the plasma, where it is bound to an α-globulin carrier protein named the vitamin D-binding protein. [ 194 ] Calcifediol is transported to the proximal tubules of the kidneys, where it is hydroxylated at the 1-α position (lower right of the molecule) to form calcitriol (1,25-dihydroxycholecalciferol, 1 ...
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- 1540 Olentangy River Rd, Columbus, OH · Directions · (614) 299-2253