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Its deficiency can cause neurodevelopmental problems which can be partly reversible with early treatment. [27] Only a small subset of dementia cases have been found to be reversible with vitamin B 12 therapy. [28] Tinnitus may be associated with vitamin B 12 deficiency. [29] Vitamin B 12 deficiency may accompany certain eating disorders or ...
Neuropsychiatric symptoms can precede hematological signs and are often the presenting manifestation of the disease. [55] Vitamin B 12 serum levels are used to detect its deficiency, but do not distinguish its causes. Vitamin B 12 levels can be falsely high or low and data for sensitivity and specificity vary widely.
Adults need about 2.4 micrograms of B12 a day (that much can be found in one portion of salmon, canned tuna or ground beef), with pregnant and nursing women needing slightly more (2.6 and 2.8 mcg ...
Other causes of low white blood cell count include systemic lupus erythematosus, Hodgkin's lymphoma, some types of cancer, typhoid, malaria, tuberculosis, dengue, rickettsial infections, enlargement of the spleen, folate deficiencies, psittacosis, sepsis, Sjögren syndrome and Lyme disease.
Pernicious anaemia is a lifelong condition that affects nearly 5 in 100,000 people in the UK.
B12 also tamps down chronic inflammation within the cardiovascular system (that can, in turn, lower heart disease risk), helps maintain the nervous system (including the myelin sheath ...
A low level of blood Vitamin B 12 is a finding that normally can and should be treated by injections, supplementation, or dietary or lifestyle advice, but it is not a diagnosis. Hypovitaminosis B 12 can result from a number of mechanisms, including those listed above. For determination of cause, further patient history, testing, and empirical ...
Acute myeloid leukemia (AML), also known as acute myelogenous leukemia, is a cancer of the myeloid line of blood cells, characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells. [81] Polycythemia vera: Acute promyelocytic leukemia: Acute basophilic ...