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Young boy displaying the characteristic maculopapular rash of rubella [10] Generalized rash on the abdomen due to rubella Rubella has symptoms similar to those of flu. However, the primary symptom of rubella virus infection is the appearance of a rash (exanthem) on the face which spreads to the trunk and limbs and usually fades after three days ...
The 1962–1965 rubella epidemic was an outbreak of rubella across Europe and the United States. [ 1 ] [ 2 ] The Rubella virus, also known as the German measles, is a single-stranded RNA virus from the family Togaviridae and genus Rubivirus . [ 3 ]
The genome encodes several non-coding RNA structures; among them is the rubella virus 3' cis-acting element, which contains multiple stem-loops, one of which has been found to be essential for viral replication. [12] The only significant region of homology between rubella and the alphaviruses is located at the NH2 terminus of non structural ...
This type of rash is common in several diseases and medical conditions, including scarlet fever, measles, Ebola virus disease, rubella, HIV, secondary syphilis (Congenital syphilis, which is asymptomatic, the newborn may present this type of rash), erythrovirus (parvovirus B19), chikungunya (alphavirus), zika, smallpox (which has been ...
Congenital rubella syndrome (CRS) occurs when a human fetus is infected with the rubella virus (German measles) via maternal-fetal transmission and develops birth defects. [1] The most common congenital defects affect the ophthalmologic, cardiac, auditory, and neurologic systems.
Rubella, ("German measles") identified in 1881. [3] "third disease" rubella virus: Pink macules and papules that appear first on the head and spread down over body in 24 hours. Rash disappears in 2-3 days. Enanthem: Forcheimmer sign (punctate petechiae on soft palate or uvula) Erythema infectiosum, identified as a distinct condition in 1896. [13]
Forchheimer spots are a type of enanthem seen as tiny red spots on the soft palate in rubella, measles and scarlet fever. [1] They sometimes precede the skin rash of rubella. [1] The spots may be present in around 20% of people with rubella. [1] The sign is named after Frederick Forchheimer. [2]
The blueberry muffin rash was originally considered pathognomonic of congenital rubella, but it is now considered to be potentially associated with many other intrauterine infections, hematologic diseases, and malignancies. [3] Other TORCH infections that can cause this rash include cytomegalovirus, [5] herpes virus, and