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Haemophilia (British English), or hemophilia (American English) [6] (from Ancient Greek αἷμα (haîma) 'blood' and φιλία (philía) 'love of'), [7] is a mostly inherited genetic disorder that impairs the body's ability to make blood clots, a process needed to stop bleeding.
Treatment Factor VIII, factor VIII inhibitors, emicizumab Haemophilia A (or hemophilia A ) is a blood clotting disorder caused by a genetic deficiency in clotting factor VIII , thereby resulting in significant susceptibility to bleeding, both internally and externally.
Haemophilia B, also spelled hemophilia B, is a blood clotting disorder causing easy bruising and bleeding due to an inherited mutation of the gene for factor IX, and resulting in a deficiency of factor IX. It is less common than factor VIII deficiency (haemophilia A). [3] Haemophilia B was first recognized as a distinct disease entity in 1952. [4]
Hemophilia is a family of rare genetic blood diseases caused by a clotting factor deficiency (FVIII in hemophilia A, FIX in hemophilia B), impacting more than 800,000 people globally.
Acquired haemophilia A (AHA) is a rare but potentially life-threatening bleeding disorder characterized by autoantibodies directed against coagulation factor VIII.These autoantibodies constitute the most common spontaneous inhibitor to any coagulation factor and may induce spontaneous bleeding in patients with no previous history of a bleeding disorder.
Treatment tranexamic acid [ 3 ] Haemophilia C (also known as plasma thromboplastin antecedent (PTA) deficiency or Rosenthal syndrome ) is a mild form of haemophilia affecting both sexes, due to factor XI deficiency . [ 4 ]
Hemophilia remains a complex disease to manage and various non-profit organizations are engaged in patient advocacy by spreading awareness about disease symptoms and newer treatment alternatives. Furthermore, market leaders are continuously focusing on R&D activities to develop novel drugs with improved safety, efficacy and convenience of ...
The National Bleeding Disorders Foundation (NBDF) is a United States patient advocacy organization for the care and treatment of inheritable blood and bleeding disorders such as hemophilia and von Willebrand disease. Founded in 1948, NBDF, then known as the National Hemophilia Foundation, helps secure funding for treatment centers and develops ...
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